Evidence map›Paper›PMID 36213437›Full record

ArticleThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale2022

SARS-CoV-2 in the Air Surrounding Patients during Nebulizer Therapy.

Jostein Gohli, Arne Broch Brantsæter, Kari Oline Bøifot, Carola Grub, Beathe Kiland Granerud, Jan Cato Holter, Anne Margarita Dyrhol Riise, Madelen Foss Smedholen, Marius Dybwad

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Jostein GohliNorwegian Defence Research Establishment, P. O. Box 25, No. 2027 Kjeller, Oslo, Norway.ORCID https://orcid.org/0000-0002-7273-1860
Arne Broch BrantsæterDepartment of Infectious Diseases, Oslo University Hospital, P. O. Box 4956, Nydalen, No. 0424, Oslo, Norway.
Kari Oline BøifotNorwegian Defence Research Establishment, P. O. Box 25, No. 2027 Kjeller, Oslo, Norway.
Carola GrubInstitute of Microbiology, Norwegian Armed Forces Joint Medical Services, P. O. Box 25, No. 2027, Kjeller, Oslo, Norway.
Beathe Kiland GranerudDepartment of Microbiology, Oslo University Hospital, P. O. Box 4950, Blindern, No. 0424, Oslo, Norway.ORCID https://orcid.org/0000-0002-6951-2317
Jan Cato HolterDepartment of Microbiology, Oslo University Hospital, P. O. Box 4950, Blindern, No. 0424, Oslo, Norway.
Anne Margarita Dyrhol RiiseDepartment of Infectious Diseases, Oslo University Hospital, P. O. Box 4956, Nydalen, No. 0424, Oslo, Norway.
Madelen Foss SmedholenOslo University Hospital, P. O. Box 4950, Nydalen, No. 0424, Oslo, Norway.
Marius DybwadNorwegian Defence Research Establishment, P. O. Box 25, No. 2027 Kjeller, Oslo, Norway.
Oslo University Hospital · NONorwegian Defence Research Establishment · NONorwegian Armed Forces · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nebulizer therapy is commonly used for patients with obstructive pulmonary disease or acute pulmonary infections with signs of obstruction. It is considered a "potential aerosol-generating procedure," and the risk of disease transmission to health care workers is uncertain. The aim of this pilot study was to assess whether nebulizer therapy in hospitalized COVID-19 patients is associated with increased dispersion of SARS-CoV-2. Air samples collected prior to and during nebulizer therapy were analyzed by RT-PCR and cell culture. Total aerosol particle concentrations were also quantified. Of 13 patients, seven had quantifiable virus in oropharynx samples, and only two had RT-PCR positive air samples. For both these patients, air samples collected during nebulizer therapy had higher SARS-CoV-2 RNA concentrations compared to control air samples. Also, for particle sizes 0.3-5

Identifiers

PMID36213437
PMCPMC9536972
OpenAlexW4296157849

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.