Evidence map›Paper›PMID 36213271›Full record

ArticleFrontiers in endocrinology2022

Evaluation of bone mineral density and body compositions interrelation in young and middle-aged male patients with Crohn's disease by quantitative computed tomography.

Xueli Zhang, Kun Peng, Gang Li, Lidi Wan, Tingting Xu, Zhijun Cui, Fuxia Xiao, Li Li, Zhanju Liu, Lin Zhang and 1 more

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In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xueli ZhangDepartment of Radiology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
Kun PengDepartment of Radiology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
Gang LiDepartment of Radiology, Shanghai East Hospital, Tongji University of Medicine, Shanghai, China.
Lidi WanDepartment of Radiology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
Tingting XuDepartment of Radiology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
Zhijun CuiDepartment of Radiology, Chongming branch of Shanghai Tenth People's Hospital, Shanghai, China.
Fuxia XiaoDepartment of Radiology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
Li LiDepartment of Radiology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
Zhanju LiuDepartment of Gastroenterology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
Lin ZhangDepartment of Radiology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
Guangyu TangDepartment of Radiology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The aim of this study was to investigate the characteristics of bone mineral density (BMD) and body compositions, and the impact of body compositions on BMD in young and middle-aged male patients with Crohn's disease (CD). Methods: Patients with CD (n = 198) and normal controls (n = 123) underwent quantitative computed tomography (QCT) examination of lumbar vertebrae 1-3 (L1-3). The BMD and bone geometric parameters were measured and outputted by QCT post-process software. Meanwhile, body composition parameters, including subcutaneous adipose tissue (SAT), visceral adipose tissue (VAT), lean mass (LM), and muscles mass around lumbar vertebrae were also acquired by QCT. Blood indicators [interleukin (IL)-6, IL-8, tumor necrosis factor alpha (TNF-α), C-reactive protein (CRP), Ca, and P] were collected from clinical medical records. Independent Results: There was no significant difference in age, height, and weight between the CD group and the control group ( Conclusions: Patients with CD could suffer from reduction in BMD. However, the parameters of bone geometric parameters are more sensitive and accurate than BMD changes. Among them, Tb. BMD, VAT, Ct. Ar, and LM have significant effects on BMD reduction.

Indexed as

Bone DensityCrohn DiseaseBody CompositionC-Reactive ProteinHumansInterleukin-6Interleukin-8MaleMiddle AgedTomography, X-Ray ComputedTumor Necrosis Factor-alphaC-Reactive ProteinInterleukin-6Interleukin-8Tumor Necrosis Factor-alphabody compositionsbone geometric parametersbone mineral densityCrohn’s diseasequantitative computed tomography

Identifiers

PMID36213271
PMCPMC9537810

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.