Evidence map›Paper›PMID 36213264›Full record

ArticleFrontiers in endocrinology2022

A functional polymorphism of microRNA-143 is associated with the risk of type 2 diabetes mellitus in the northern Chinese Han population.

Dexian Kong, Ya Duan, Jinli Wang, Yabin Liu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Dexian KongDepartment of Endocrinology, Fourth Affiliated Hospital, Hebei Medical University, Shijiazhuang, China.
Ya DuanDepartment of Obstetrics, Hebei General Hospital, Shijiazhuang, China.
Jinli WangDepartment of Infirmary, Hebei Public Security Police Vocational College, Shijiazhuang, China.
Yabin LiuDepartment of General Surgery, Fourth Affiliated Hospital, Hebei Medical University, Shijiazhuang, China.
Hebei Medical University · CNHebei General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the association between two polymorphisms of microRNA-143 (miR-143) and the risk of type 2 diabetes mellitus (T2DM) in the northern Chinese Han population. Study Design: This case-control study involved 326 patients with T2DM and 342 healthy controls. Two genetic variants (rs4705342 and rs353292) of Results: The CC genotype frequency of rs4705342 was significantly higher in the T2DM patients than in the healthy controls ( Conclusion: The CC genotype of rs4705342 might be a risk factor for developing T2DM by increasing the expression of miRNA-143 in the northern Chinese Han population.

Indexed as

Diabetes Mellitus, Type 2MicroRNAsBlood GlucoseCase-Control StudiesChinaCholesterol, LDLGenetic Predisposition to DiseaseGlycated HemoglobinHumansLigasesPolymorphism, Single NucleotideBlood GlucoseCholesterol, LDLGlycated HemoglobinLigasesMicroRNAsMIRN143 microRNA, humanexpressionMiRNA-143polymorphismrisktype 2 diabetes mellitus

Identifiers

PMID36213264
PMCPMC9538736
OpenAlexW4296828227

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.