ArticleInternational journal of endocrinology2022
Analysis of the Incidence and Risk Factors of Precocious Puberty in Girls during the COVID-19 Pandemic.
Article in International journal of endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Comparison of central precocious puberty frequency before and during COVID-19: a systematic review and meta-analysis.BMC endocrine disorders · 2024Pooled it
- Association between vitamin D and central precocious puberty in children: Threshold effects and mediation mechanisms based on LC-MS/MS quantitation.Journal of endocrinological investigation · 2026Article
- Central precocious puberty in Türkiye, 2018-2024: national incidence, prevalence, and changes across the COVID-19 period.Frontiers in endocrinology · 2026Article
- Trends in central precocious puberty incidence in Japan during the COVID-19 pandemic.Frontiers in pediatrics · 2026Article
- Impact of the COVID-19 pandemic on the incidence of central precocious puberty: A PRISMA-ScR-COMPLIANT scoping review.Archives of endocrinology and metabolism · 2025Article
- A review of vitamin D deficiency and vitamin D receptor polymorphisms in endocrine-related disorders.Clinical and experimental pediatrics · 2025Article
- Back to normal? A retrospective study on stimulation test and endocrinological diagnosis before, during and after COVID-19 pandemics.Frontiers in endocrinology · 2025Article
- Investigation of vitamin D deficiency in girls with growth and development variations-a single center study.Frontiers in pediatrics · 2025Article
- Article
- Central Precocious Puberty During the COVID-19 Pandemic Period: A Systematic Review of Literature.Cureus · 2024Review
- Polymorphism rs5780218, rs12998 and rs10158616 in KISS1 gene among the Hubei province Chinese girls with the central precocious puberty.Endocrine · 2024Article
- Joint association of overweight/obesity, high electronic screen time, and low physical activity time with early pubertal development in girls: a case-control study.Scientific reports · 2024Article
- Dietary pattern and precocious puberty risk in Chinese girls: a case-control study.Nutrition journal · 2024Article
- Pineal cysts may promote pubertal development in girls with central precocious puberty: a single-center study from China.Frontiers in endocrinology · 2024Article
- Interaction between Vitamin D homeostasis, gut microbiota, and central precocious puberty.Frontiers in endocrinology · 2024Review
- Multi-omic analysis of precocious puberty girls: pathway changes and metabolite validation.Frontiers in endocrinology · 2024Article
- Endocrinological Involvement in Children and Adolescents Affected by COVID-19: A Narrative Review.Journal of clinical medicine · 2023Review
- Precocious Puberty Diagnoses Spike, COVID-19 Pandemic, and Body Mass Index: Findings From a 4-year Study.Journal of the Endocrine Society · 2023Article
- Is blue light exposure a cause of precocious puberty in male rats?Frontiers in endocrinology · 2023Article
- Precocious puberty under stressful conditions: new understanding and insights from the lessons learnt from international adoptions and the COVID-19 pandemic.Frontiers in endocrinology · 2023Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Home quarantine due to the global coronavirus disease 2019 (COVID-19) pandemic has had a significant impact on children. Lifestyle changes have led to an increase in precocious puberty (PP) among girls, and the underlying risk factors for this remain unclear. Thus, we aimed to assess the influence of environmental, genetic, nutritional, and other lifestyle factors on the risk of PP in girls. We evaluated the incidence of new-onset PP in girls during home quarantine for COVID-19 and analyzed the potential risk factors. This was a retrospective questionnaire and medical record-based study involving 22 representative medical units from 13 cities in Henan Province, China. Girls with new-onset PP (central precocious puberty, 58; premature thelarche, 58; age, 5-9 years) between February 2020 and May 2020 were included, along with 124 healthy, age-matched controls. The number of new-onset PP cases reported during the study period was compared with that reported between February and May in 2018 and 2019. Patients' families completed a questionnaire to assess potential risk factors. There was a 5.01- and 3.14-fold increase in the number of new-onset PP cases from 2018 to 2020 and from 2019 to 2020, respectively; the differences were statistically significant (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.