ArticleFrontiers in bioengineering and biotechnology2022
Biohybrid elastin-like venous valve with potential for
Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 26 citations in OpenAlex.
- A Versatile Engineering Platform for the Fabrication of Prosthetic Venous Valves Using Electrospinning.Advanced healthcare materials · 2026Article
- Small patients - Big needs: A material-based approach to develop miniaturised valves for congenital heart diseases.Bioactive materials · 2026Article
- Biohybrid microvascular interponates with integrated elastin-like recombinamers - validation of stability and biomimetic elasticity in human vessels.Scientific reports · 2025Article
- Combined Effects of Diosmin, Hesperidin,International journal of molecular sciences · 2025Article
- Bioorthogonal Mussel-Inspired Elastin-like Nanocoatings for Indwelling Devices.ACS applied materials & interfaces · 2025Article
- Biohybrid Vascular Graft Made of Textile-Reinforced Elastin-Like Recombinamers and Its Preservation via Drying Processes.Advanced healthcare materials · 2025Article
- Advances in the diagnosis and treatment of primary deep venous valve insufficiency.European journal of medical research · 2025Review
- Elastic, load-bearing and autoclavable protein-based graft for coronary revascularization.Frontiers in bioengineering and biotechnology · 2025Article
- Contribution of the ELRs to the development of advancedFrontiers in bioengineering and biotechnology · 2024Review
- Lifelike Transformative Materials for Biohybrid Implants: Inspired by Nature, Driven by Technology.Advanced healthcare materials · 2023Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic venous insufficiency (CVI) is a leading vascular disease whose clinical manifestations include varicose veins, edemas, venous ulcers, and venous hypertension, among others. Therapies targeting this medical issue are scarce, and so far, no single venous valve prosthesis is clinically available. Herein, we have designed a bi-leaflet transcatheter venous valve that consists of (i) elastin-like recombinamers, (ii) a textile mesh reinforcement, and (iii) a bioabsorbable magnesium stent structure. Mechanical characterization of the resulting biohybrid elastin-like venous valves (EVV) showed an anisotropic behavior equivalent to the native bovine saphenous vein valves and mechanical strength suitable for vascular implantation. The EVV also featured minimal hemolysis and platelet adhesion, besides actively supporting endothelialization
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.