ArticleFrontiers in bioengineering and biotechnology2022
PCL strut-like scaffolds appear superior to gyroid in terms of bone regeneration within a long bone large defect: An
Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Article
- Development of a subject-specific finite element analysis workflow to assess local biomechanics during segmental bone defect healing.Journal of the mechanical behavior of biomedical materials · 2025Article
- Impact of Particle Size and Sintering Temperature on Calcium Phosphate Gyroid Structure Scaffolds for Bone Tissue Engineering.Journal of functional biomaterials · 2024Article
- 3D-Printed Osteoinductive Polymeric Scaffolds with Optimized Architecture to Repair a Sheep Metatarsal Critical-Size Bone Defect.Advanced healthcare materials · 2023Article
- Geometric Mismatch Promotes Anatomic Repair in Periorbital Bony Defects in Skeletally Mature Yucatan Minipigs.Advanced healthcare materials · 2023Article
- Article
- Computational design and evaluation of the mechanical and electrical behavior of a piezoelectric scaffold: a preclinical study.Frontiers in bioengineering and biotechnology · 2023Article
- AnFrontiers in bioengineering and biotechnology · 2023Article
- Novel 3D printed TPMS scaffolds: microstructure, characteristics and applications in bone regeneration.Journal of tissue engineeringReview
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The treatment of large bone defects represents a major clinical challenge. 3D printed scaffolds appear as a promising strategy to support bone defect regeneration. The 3D design of such scaffolds impacts the healing path and thus defect regeneration potential. Among others, scaffold architecture has been shown to influence the healing outcome. Gyroid architecture, characterized by a zero mean surface curvature, has been discussed as a promising scaffold design for bone regeneration. However, whether gyroid scaffolds are favourable for bone regeneration in large bone defects over traditional strut-like architecture scaffolds remains unknown. Therefore, the aim of this study was to investigate whether gyroid scaffolds present advantages over more traditional strut-like scaffolds in terms of their bone regeneration potential. Validated bone defect regeneration principles were applied in an
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