ArticleEvidence-based complementary and alternative medicine : eCAM2022
Identification of Diagnostic Biomarkers of Rape Pollen Allergy Based on MRNA Sequencing.
Article in Evidence-based complementary and alternative medicine : eCAM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 3 citations in OpenAlex.
- Retracted: Identification of Diagnostic Biomarkers of Rape Pollen Allergy Based on MRNA Sequencing.Evidence-based complementary and alternative medicine : eCAM · 2023Article
Corrections and comments
- Retraction · 2023-08-02Concerns/Issues about Data · Concerns/Issues about Results and/or Conclusions · Concerns/Issues about Referencing/Attributions · Concerns/Issues about Peer Review · Investigation by Journal/Publisher · Investigation by Third Party · Computer-Aided Content or Computer-Generated Content · Unreliable Results and/or Conclusions · · See also: https://pubpeer.com/publications/457097A7684BDBF9FDD69E5CDB2D02
- Retracted
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, 383 differentially expressed genes (DEGs) between the allergic group and the nonallergic group were excavated. Humoral immune response, chemokine-related biological processes, granulocyte-related biological processes, IL-17 signaling pathway, and TNF signaling pathway were found connected with DEGs. The allergic group had significantly higher enrich scores of T cells, T helper cells, TFH, and Th17 cells than the nonallergic group. We acquired 26 rape pollen allergy-associated genes by taking the intersection of key module genes from WGCNA and the DEGs. The functional enrichment results show that rape pollen allergy-associated genes are relevant to processes and pathways like regulation of inflammatory response, transcriptional regulation, lymphocyte differentiation, IL-17 signaling pathway, and MAPK signaling pathway. Then, three characteristic genes were defined by crossing the genes derived from LASSO and SVM-RFE algorithms, including
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.