Evidence map›Paper›PMID 36212971›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2022

miR-28-5p's Targeting of GAGE12I Inhibits Proliferation, Migration, and Invasion of Gastric Cancer in Vitro.

Ruizhe Xu, Qi Guo, Peifeng Zhao, Haiyan Lu, Bo Zhang

RetractedAbstract readRetracted Publication
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Ruizhe XuDepartment of Radiotherapy & Oncology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Qi GuoDepartment of Radiotherapy & Oncology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Peifeng ZhaoDepartment of Radiotherapy & Oncology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Haiyan LuDepartment of Radiotherapy & Oncology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Bo ZhangDepartment of Radiotherapy & Oncology, The Second Affiliated Hospital of Soochow University, Suzhou, China.ORCID https://orcid.org/0000-0002-4865-0665

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

GAGE12I is a tumor metastasis-promoting factor, which can induce gastric cancer cells to invade and migrate. We investigated the effect of miR-28-5p targeting GAGE12I on proliferation, invasion, and migration of human gastric cancer cell lines SGC-7901, AGS, and MGC-803. The expression levels of miR-28-5p and GAGE12I were detected by real-time PCR and western blot, respectively. Cell proliferation, migration, and invasion were measured by MTT and Transwell chamber. The interaction between miR-28-5p and GAGE12I was investigated by bioinformatics analysis and luciferase assay. Results showed that the expression of miR-28-5p in human gastric cancer cell lines was lower than that in normal gastric epithelial cells (

Identifiers

PMID36212971
PMCPMC9546678

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.