ArticleJournal of lipid and atherosclerosis2022
The Atherogenic Index of Plasma is Associated With Cerebral Small Vessel Disease: A Cross-Sectional Study.
Article in Journal of lipid and atherosclerosis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Associations Between Serum Selenium, Zinc, and Copper Levels and Cognitive Function in the Elderly.Nutrients · 2025Article
- The association between atherogenic index of plasma and cognitive impairment among older adults in Southern Iran: findings from the Bushehr elderly health program.BMC geriatrics · 2025Article
- Atherogenic and Inflammatory Markers in Recent Small Subcortical Infarcts: Associations with Location, Morphology, and Short-Term Recurrence.Journal of inflammation research · 2025Article
- Association between carotid atherosclerotic plaque characteristics and white matter hyperintensity in cerebral small vessel disease.Frontiers in neurology · 2025Article
- Association of novel lipid indices with the white matter hyperintensities in cerebral small vessel disease: a cross-sectional study.Lipids in health and disease · 2024Article
- Are OnlyJournal of lipid and atherosclerosis · 2023Article
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Authors and funding
4 authors.
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Abstract
Objective: Recently, the lipid profile of atherogenic dyslipidemia has become important in cerebrovascular diseases. Atherogenic index of plasma (AIP), an index that reflects this lipid profile as a single number, has been proposed, but there are still few related studies in cerebrovascular disease. In this study, we evaluated the relationship between AIP and cerebral small vessel disease (cSVD) in health check-up participants. Methods: We assessed consecutive health check-ups participants between 2006 and 2013. cSVD was measured including the following three subtypes: white matter hyperintensity (WMH), lacuens, and cerebral microbleeds (CMBs). WMH quantitatively measured the volume, and lacunes and CMBs qualitatively evaluated the presence. AIP was calculated according to the following formula based on blood test results: AIP=log [triglyceride (mg/dL)/high-density lipoprotein cholesterol (mg/dL)]. Results: A total of 3,170 participants were evaluated (mean age: 56.5 years, male sex: 53.8%). In multivariable linear regression analysis, AIP ( Conclusion: High AIP was associated with cSVD in health check-up participants. Since this close relationship was only seen in WMH and lacunes, these subtypes may have arisen from a more atherosclerosis-related pathology.
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