Evidence map›Paper›PMID 36212566›Full record

ArticleF&S reports2022

Patient attitudes and preferences for the management of pregnancy of unknown location.

Jessica K Wu, Emily N Sadecki, Moira A Kyweluk, Suneeta Senapati, Anne N Flynn, Elizabeth Steider, Tracey Thomas, Kurt T Barnhart

Open access · goldAbstract read
In one paragraph

Article in F&S reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jessica K WuPerelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Emily N SadeckiMayo Clinic Alix School of Medicine, Mayo Clinic, Rochester, Minnesota.
Moira A KywelukPerelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Suneeta SenapatiDepartment of Reproductive Endocrinology and Infertility, University of Pennsylvania, Philadelphia, Pennsylvania.
Anne N FlynnDepartment of Obstetrics and Gynecology, University of California Davis, Sacramento, California.
Elizabeth SteiderWomen's Health Clinical Research Center, University of Pennsylvania, Philadelphia, Pennsylvania.
Tracey ThomasWomen's Health Clinical Research Center, University of Pennsylvania, Philadelphia, Pennsylvania.
Kurt T BarnhartDepartment of Reproductive Endocrinology and Infertility, University of Pennsylvania, Philadelphia, Pennsylvania.
University of Pennsylvania · USMayo Clinic · USUniversity of California, Davis · US

Funding

Development of a serum biosignature for ectopic pregnancy.R01HD076279 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI BARNHART, KURT T · 2014 to 2018
$3.4M
NICHD NIH HHS R01 HD076279
6 · The paper itself

Abstract

Objective: To understand patient attitudes and preferences when faced with the uncertainty of pregnancy of unknown location (PUL). Design: Qualitative, interview-based study. Setting: University Hosptial. Patients: Patients aged >18 years sampled from the emergency department and a subspecialty fertility practice of a university hospital system. Interventions: Six to 8 weeks after resolution of a PUL, with an ultimate clinical outcome of either an intrauterine pregnancy, spontaneous abortion, or ectopic pregnancy. Participants underwent either surgical, medical, or expectant management. Main Outcome Measures: Thematic analysis of the virtual, semistructured interviews (45-60 minutes in length) conducted with participants to identify commonly expressed priorities was performed. Results: Interviews were completed from October 2020 to March 2021 until thematic saturation was achieved (n = 15). Resolution diagnoses included intrauterine pregnancy (26.7%, n = 4), ectopic pregnancy (40.0%, (n = 6), and spontaneous abortion (33.3%, n = 5). Moreover, 66.7% (n = 10) of the patients presented to the emergency department, whereas 33.3% (n = 5) presented to a subspecialty fertility clinic. All had desired pregnancies. Thematic analyses revealed 4 related priorities around PUL management: Conclusions: These data demonstrate novel themes around related priorities in patients with desired pregnancies diagnosed with a PUL previously underappreciated by clinicians. The balance of these priorities evolved throughout management with increasing information and clarity. Continually reevaluating relevant patient priorities and preferences is essential to the comprehensive management of PUL.

Indexed as

abortionectopicPregnancy unknown location

Identifiers

PMID36212566
PMCPMC9532885
OpenAlexW4284991361

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.