Evidence map›Paper›PMID 36212502›Full record

ReviewFrontiers in oncology2022

Drug resistance in multiple myeloma: Soldiers and weapons in the bone marrow niche.

Antonio Giovanni Solimando, Eleonora Malerba, Patrizia Leone, Marcella Prete, Carolina Terragna, Michele Cavo, Vito Racanelli

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 4 pooled it
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 4 syntheses or guidelines pooled it, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Antonio Giovanni SolimandoDepartment of Biomedical Sciences and Human Oncology, School of Medicine, 'Aldo Moro' University of Bari, Bari, Italy.
Eleonora MalerbaDepartment of Biomedical Sciences and Human Oncology, School of Medicine, 'Aldo Moro' University of Bari, Bari, Italy.
Patrizia LeoneDepartment of Biomedical Sciences and Human Oncology, School of Medicine, 'Aldo Moro' University of Bari, Bari, Italy.
Marcella PreteDepartment of Interdisciplinary Medicine, School of Medicine, 'Aldo Moro' University of Bari, Bari, Italy.
Carolina Terragna'Seràgnoli' Institute of Hematology, Bologna University School of Medicine, Bologna, Italy.
Michele Cavo'Seràgnoli' Institute of Hematology, Bologna University School of Medicine, Bologna, Italy.
Vito RacanelliDepartment of Interdisciplinary Medicine, School of Medicine, 'Aldo Moro' University of Bari, Bari, Italy.
University of Bari Aldo Moro · ITIstituto Tumori Bari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple myeloma (MM) is still an incurable disease, despite considerable improvements in treatment strategies, as resistance to most currently available agents is not uncommon. In this study, data on drug resistance in MM were analyzed and led to the following conclusions: resistance occurs

Indexed as

bone marrow microenvironmentdrug resistancemonoclonal gammopathy of undetermined significancemultiple myelomatherapeutic targets

Identifiers

PMID36212502
PMCPMC9533079
OpenAlexW4296737731

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.