Evidence map›Paper›PMID 36212270›Full record

ReviewCureus2022

Efficacy of Anakinra in Pericarditis: A Systematic Review.

Ameer Haider Cheema, Keyur Chaludiya, Maham Khalid, Marcellina Nwosu, Srujana Konka, Walter Y Agyeman, Aakash Bisht, Ankit Gopinath, Ana P Arcia Franchini

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ameer Haider CheemaInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Keyur ChaludiyaInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Maham KhalidInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Marcellina NwosuInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Srujana KonkaInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Walter Y AgyemanInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Aakash BishtInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Ankit GopinathInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Ana P Arcia FranchiniResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
California Institute of Behavioral Neurosciences and Psychology (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation of the pericardium is referred to as pericarditis, which can cause sharp chest pain and has a high chance of recurrence even after treatment. This review will explore anakinra, which is an interleukin-1 receptor antagonist, as a potential new treatment for pericarditis. The systematic review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines by searching PubMed and GoogleScholar from the years 2012 to 2022. After applying inclusion and exclusion criteria, thorough screening, and quality appraisal, a total of eleven studies were included in the review; eight case reports and three clinical trials. All studies showed that 100 mg/day of anakinra caused a remarkable improvement in patient outcomes. In addition, the pericarditis resolved quicker and had a lower chance of recurrence in comparison to conventional therapy.

Indexed as

anakinraanti-interleukin-1 treatmentidiopathic pericarditisinterleukin-1 inhibitorrecurrent pericarditistreatment resistant pericarditis

Identifiers

PMID36212270
PMCPMC9531702
OpenAlexW4300865300

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.