Evidence map›Paper›PMID 36212238›Full record

ArticleACG case reports journal2022

Increasing Alkaline Phosphatase as the Primary Manifestation of Disseminated Histoplasmosis in an AIDS Patient Without Pulmonary Disease.

Triston Berger, Sebastian Borja, Jonathan Kandiah, Jaspreet Suri, Harvey Riback

Abstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Triston BergerDepartment of Internal Medicine, Norwalk Hospital, Affiliated with Yale School of Medicine, Norwalk, CT.
Sebastian BorjaDepartment of Internal Medicine, Norwalk Hospital, Affiliated with Yale School of Medicine, Norwalk, CT.
Jonathan KandiahDivision of Gastroenterology and Hepatology, Norwalk Hospital, Affiliated with Yale School of Medicine, Norwalk, CT.
Jaspreet SuriDivision of Gastroenterology and Hepatology, Norwalk Hospital, Affiliated with Yale School of Medicine, Norwalk, CT.
Harvey RibackDivision of Gastroenterology and Hepatology, Norwalk Hospital, Affiliated with Yale School of Medicine, Norwalk, CT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Histoplasmosis is an infection caused by the dimorphic fungi Histoplasma. Hepatic involvement in the setting of disseminated histoplasmosis from a pulmonary source is well documented. Hepatic involvement as the primary manifestation in the absence of pulmonary disease is rare. We present a patient with acquired immune deficiency syndrome found to have disseminated histoplasmosis with worsening alkaline phosphatase as the primary manifestation of disease, which has not been reported in a review of the literature. After diagnosis, the patient was started on appropriate therapy with alkaline phosphatase return to baseline.

Identifiers

PMID36212238
PMCPMC9534362

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.