Evidence map›Paper›PMID 36212050›Full record

ReviewTherapeutics and clinical risk management2022

Impulse Oscillometry, Small Airways Disease, and Extra-Fine Formulations in Asthma and Chronic Obstructive Pulmonary Disease: Windows for New Opportunities.

Alfredo Chetta, Nicola Facciolongo, Cosimo Franco, Laura Franzini, Alessio Piraino, Carmelina Rossi

Open access · goldAbstract readReview
In one paragraph

Review in Therapeutics and clinical risk management, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. The Impact of Age and Disease Entity on Small Airway Dysfunction in Obstructive Airway Diseases.International journal of chronic obstructive pulmonary disease · 2025
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Alfredo ChettaClinica Pneumologica, Università di Parma, Parma, Italy.ORCID 0000-0002-0416-5334
Nicola FacciolongoUOC Pneumologia, Arcispedale Santa Maria Nuova, Reggio Emilia, Italy.
Cosimo FrancoUOC Pneumologia, Ospedale Guglielmo da Saliceto, Piacenza, Italy.
Laura FranziniChiesi Italia SpA, Medical Affairs, Parma, Italy.
Alessio PirainoChiesi Italia SpA, Medical Affairs, Parma, Italy.ORCID 0000-0002-8029-2159
Carmelina RossiChiesi Italia SpA, Medical Affairs, Parma, Italy.
Chiesi (Italy) · ITGuglielmo da Saliceto Hospital · ITOspedale Santa Maria · ITUniversity of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, the perspective of management of respiratory disease has been gradually changing in light of the increasing evidence of small airways as the major site of airflow obstruction contributing to the development of both COPD and asthma already in early stages of disease. First and foremost, the evidence is redefining disease severity, identifying small airways disease phenotypes and early signs of disease, and revising prevalence and overall epidemiological data as well. Much effort has been put toward the instrumental assessment of small airways' involvement and early detection. Several clinical trials have evaluated the advantage of extra-fine formulations which can best target the small airways in uncontrolled asthma and severe COPD. Here, we briefly present a practical overview of the role of the small airways in disease, the most appropriate diagnostic methods for quantifying their impairment, and provide some insight into the costs of respiratory management in Italy, especially in sub-optimally controlled disease.

Indexed as

asthmachronic obstructive pulmonary diseasecostextrafine particlesimpulse oscillometrysmall airways

Identifiers

PMID36212050
PMCPMC9533783
OpenAlexW4298120565

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.