Evidence map›Paper›PMID 36212048›Full record

ArticleTherapeutics and clinical risk management2022

Correlations Between Coronary Artery Disease, Coronary Artery Calcium Score, and Lipoprotein(a) Level in Korea.

Joan Kim, Seung Woo Choi, Young Shin Lee, Jung Myung Lee, Hyemoon Chung, Jong Shin Woo, Woo-Shik Kim, Yun Young Choi, Weon Kim

Abstract read
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Article in Therapeutics and clinical risk management, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Joan KimDepartment of Cardiology, Kyung Hee University Hospital, Seoul, Korea.ORCID 0000-0002-6108-7547
Seung Woo ChoiDepartment of Cardiology, Kyung Hee University Hospital, Seoul, Korea.ORCID 0000-0002-0233-4181
Young Shin LeeDepartment of Cardiology, Kyung Hee University Hospital, Seoul, Korea.ORCID 0000-0002-8460-1959
Jung Myung LeeDepartment of Cardiology, Kyung Hee University Hospital, Seoul, Korea.ORCID 0000-0002-1904-5335
Hyemoon ChungDepartment of Cardiology, Kyung Hee University Hospital, Seoul, Korea.ORCID 0000-0002-5615-6245
Jong Shin WooDepartment of Cardiology, Kyung Hee University Hospital, Seoul, Korea.ORCID 0000-0003-0535-1742
Woo-Shik KimDepartment of Cardiology, Kyung Hee University Hospital, Seoul, Korea.ORCID 0000-0002-3345-1137
Yun Young ChoiDepartment of Medicine, Graduate School, Kyung Hee University, Seoul, Korea.ORCID 0000-0002-6228-6636
Weon KimDepartment of Cardiology, Kyung Hee University Hospital, Seoul, Korea.ORCID 0000-0003-1264-9870

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Lipoprotein(a) (Lp(a)) levels are associated with coronary artery disease (CAD) and aortic valve calcification. This study aimed to determine the correlation between Lp(a) levels and coronary artery calcium (CAC) scores in patients who underwent coronary computed tomography angiography (CCTA). Methods: This was a single-center observational study. The patients had not been previously diagnosed with CAD and underwent CCTA and Lp(a) measurement in a three-month timeframe. Coronary angiography and further management were performed according to the physician's decision. Of the 252 patients, 81 and 171 patients underwent coronary revascularization and received medical treatment only, respectively. To examine the relationship between Lp(a) and CAC score and between Lp(a) and CAD, we divided the patients by Lp(a) level (50 mg/dL) and CAC score (400). Results: No relationship was observed between Lp(a) and CAD or other risk factors for CAD. There were no differences in the ratio of patients who underwent coronary revascularization or in the CAC score according to an Lp(a) level of 50 mg/dL. There was no difference in Lp(a) level at a CAC score of 400. The proportion of patients who underwent coronary revascularization was high in the high CAC score group (50.6% vs 23.7%, p = 0.000). No association was observed between Lp(a) level and CAC score in the Spearman correlation (0.000, p < 0.998). Conclusion: Correlations between Lp(a) level and CAC score and between Lp(a) and CAD were not observed in this Korean cohort study. However, a high CAC score was correlated with coronary revascularization.

Indexed as

coronary artery diseasecoronary calcium scorelipoprotein(a)

Identifiers

PMID36212048
PMCPMC9533785

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