Evidence map›Paper›PMID 36211997›Full record

ArticleHeliyon2022

Synthesis, spectroscopic, topological, hirshfeld surface analysis, and anti-covid-19 molecular docking investigation of isopropyl 1-benzoyl-4-(benzoyloxy)-2,6-diphenyl-1,2,5,6-tetrahydropyridine-3-carboxylate.

Arulraj Ramalingam, Murugavel Kuppusamy, Sivakumar Sambandam, Mouna Medimagh, Oluwatoba Emmanuel Oyeneyin, Amirthaganesan Shanmugasundaram, Noureddine Issaoui, Nathanael Damilare Ojo

Abstract read
In one paragraph

Article in Heliyon, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Synthesis ofPrecision chemistry · 2026
    Article
  2. Recent advances in piperidones as privileged scaffolds for drug discovery and development.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Structural basis of SARS-CoV-2 polymerase inhibition by nonnucleoside inhibitor HeE1-2Tyr.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Precision-Engineered Co-NResearch (Washington, D.C.) · 2025
    Article
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Arulraj RamalingamDepartment of Electrical and Computer Engineering, National University of Singapore, 117583, Singapore.
Murugavel KuppusamyPG & Research Department of Chemistry, Government Arts College, Chidambaram, Tamil Nadu, India.
Sivakumar SambandamResearch and Development Centre, Bharathiar University, Coimbatore 641 046, Tamil Nadu, India.
Mouna MedimaghUniversity of Monastir, Faculty of Sciences, Laboratory of Quantum and Statistical Physics (LR18ES18), Monastir, 5079, Tunisia.
Oluwatoba Emmanuel OyeneyinTheoretical and Computational Chemistry Unit, Department of Chemical Sciences Adekunle Ajasin University, Akungba Akoko, Ondo State, Nigeria.
Amirthaganesan ShanmugasundaramDepartment of Chemistry, Saveetha School of Engineering, Saveetha University, Chennai, Tamil Nadu, India.
Noureddine IssaouiUniversity of Monastir, Faculty of Sciences, Laboratory of Quantum and Statistical Physics (LR18ES18), Monastir, 5079, Tunisia.
Nathanael Damilare OjoDepartment of Chemistry, University of Ibadan, Oyo State, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Isopropyl 1-benzoyl-4-(benzoyloxy)-2,6-diphenyl-1,2,5,6-tetrahydropyridine-3-carboxylate (IDPC) was synthesized and characterized via spectroscopic (FT-IR and NMR) techniques. Hirshfeld surface and topological analyses were conducted to study structural and molecular properties. The energy gap (E

Indexed as

Density functional theoryHirshfeld surface analysisSevere acute respiratory syndrome-coronavirus diseaseTetrahydropyridine-3-carboxylateTopological analysis

Identifiers

PMID36211997
PMCPMC9526874

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.