Evidence map›Paper›PMID 36211988›Full record

ArticleMediators of inflammation2022

Homoharringtonine Attenuates Dextran Sulfate Sodium-Induced Colitis by Inhibiting NF-

Jiangrui Liu, Liangpan Shi, Wenchang Huang, Zhihua Zheng, Xiaohui Huang, Yibin Su

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Mediators of inflammation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Cancer chemoprevention: signaling pathways and strategic approaches.Signal transduction and targeted therapy · 2025
    Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jiangrui LiuDepartment of Gastrointestinal Surgery, Quanzhou First Hospital Affiliated to Fujian Medical University, No. 248 Dong Street, Licheng District, Quanzhou, 362000 Fujian, China.
Liangpan ShiDepartment of Gastrointestinal Surgery, Quanzhou First Hospital Affiliated to Fujian Medical University, No. 248 Dong Street, Licheng District, Quanzhou, 362000 Fujian, China.
Wenchang HuangDepartment of Gastrointestinal Surgery, Quanzhou First Hospital Affiliated to Fujian Medical University, No. 248 Dong Street, Licheng District, Quanzhou, 362000 Fujian, China.
Zhihua ZhengDepartment of Gastrointestinal Surgery, Quanzhou First Hospital Affiliated to Fujian Medical University, No. 248 Dong Street, Licheng District, Quanzhou, 362000 Fujian, China.
Xiaohui HuangDepartment of Gastrointestinal Surgery, Quanzhou First Hospital Affiliated to Fujian Medical University, No. 248 Dong Street, Licheng District, Quanzhou, 362000 Fujian, China.
Yibin SuDepartment of Gastrointestinal Surgery, Quanzhou First Hospital Affiliated to Fujian Medical University, No. 248 Dong Street, Licheng District, Quanzhou, 362000 Fujian, China.ORCID https://orcid.org/0000-0002-9307-8311
Fujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Homoharringtonine (HHT) exhibits an anti-inflammatory activity. The potential protective effects and mechanisms of HHT on dextran sulfate sodium- (DSS-) induced colitis were investigated. DSS-induced colitis mice were intraperitoneally injected with HHT. Body weight, colon length, disease activity index (DAI), and histopathological change were examined. The relative contents of interleukin- (IL-) 1

Indexed as

ColitisColitis, UlcerativeAnimalsAnti-Inflammatory AgentsChemokine CCL2ColonDextran SulfateHomoharringtonineHumansInterleukin-6LipopolysaccharidesMiceMice, Inbred C57BLNF-kappa BNF-KappaB Inhibitor alphaTumor Necrosis Factor-alphaAnti-Inflammatory AgentsChemokine CCL2Dextran SulfateHomoharringtonineInterleukin-6LipopolysaccharidesNF-kappa BNF-KappaB Inhibitor alphaTumor Necrosis Factor-alpha

Identifiers

PMID36211988
PMCPMC9536985
OpenAlexW4297983115

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.