Evidence map›Paper›PMID 36211976›Full record

ArticleFrontiers in cellular and infection microbiology2022

Identification of amino acid domains of

Michael W Curtis, Christa H Fierros, Beth L Hahn, Matthew C Surdel, Julie Kessler, Phillip N Anderson, Marine Vandewalle-Capo, Mari Bonde, Jieqing Zhu, Sven Bergström and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. UrinaryJournal of cellular immunology · 2025
    Article
  3. Frontiers in cellular and infection microbiology · 2024
    Article
  4. Article
  5. Allelic Variants ofMicroorganisms · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Michael W CurtisDepartment of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, WI, United States.
Christa H FierrosDepartment of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, WI, United States.
Beth L HahnDepartment of Medicine, Division of Infectious Diseases, Medical College of Wisconsin, Milwaukee, WI, United States.
Matthew C SurdelDepartment of Medicine, Division of Infectious Diseases, Medical College of Wisconsin, Milwaukee, WI, United States.
Julie KesslerDepartment of Medicine, Division of Infectious Diseases, Medical College of Wisconsin, Milwaukee, WI, United States.
Phillip N AndersonDepartment of Medicine, Division of Infectious Diseases, Medical College of Wisconsin, Milwaukee, WI, United States.
Marine Vandewalle-CapoUmeå Centre for Microbial Research, Umeå University, Umeå, Sweden.
Mari BondeUmeå Centre for Microbial Research, Umeå University, Umeå, Sweden.
Jieqing ZhuBlood Research Institute, Versiti, Milwaukee, WI, United States.
Sven BergströmUmeå Centre for Microbial Research, Umeå University, Umeå, Sweden.
Jenifer CoburnDepartment of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, WI, United States.
Medical College of Wisconsin · USUmeå University · SEVersiti Blood Center of Wisconsin · US

Funding

Structural Transition of Cellular Integrins and Applications ThereofR01HL131836 · NHLBI · VERSITI WISCONSIN, INC. · PI Jieqing Zhu · 2016 to 2026
$5.5M
The roles of Lyme spirochete adhesins in hematogenous disseminationR01AI169724 · NIAID · MEDICAL COLLEGE OF WISCONSIN · PI Jenifer L Coburn, JOHN M LEONG · 2022 to 2026
$3.6M
Functional Analyses of Borrelia burgdorferi AdhesinsR01AI118799 · NIAID · MEDICAL COLLEGE OF WISCONSIN · PI CHACONAS, GEORGE, COBURN, JENIFER L · 2016 to 2020
$3.3M
Multiple B. burgdorferi Factors Collaborate to Evade Complement-Mediated DefensesR01AI121401 · NIAID · TUFTS UNIVERSITY BOSTON · PI COBURN, JENIFER L, LEONG, JOHN M · 2016 to 2020
$3.1M
Analysis of the Borrelia burgdorferi Integrin Ligand P66R01AI084873 · NIAID · MEDICAL COLLEGE OF WISCONSIN · PI COBURN, JENIFER L · 2012 to 2016
$1.9M
Structural Mechanisms Underlying the Activity Regulation of the Receptor-like Protein Tyrosine Phosphatase, CD148/PTPRJR01GM137143 · NIGMS · VERSITI WISCONSIN, INC. · PI ZHU, JIEQING · 2020 to 2023
$1.4M
Mechanisms of Leptospira interrogans interactions with the vascular endothelium in vivoR21AI147573 · NIAID · MEDICAL COLLEGE OF WISCONSIN · PI COBURN, JENIFER L · 2020 to 2021
$435k
Investigation of the Porin Function of B. burgdorferi P66R21AI140510 · NIAID · MEDICAL COLLEGE OF WISCONSIN · PI COBURN, JENIFER L · 2019 to 2020
$424k
NHLBI NIH HHS R01 HL131836NIAID NIH HHS R01 AI084873NIAID NIH HHS R01 AI118799NIAID NIH HHS R01 AI121401NIAID NIH HHS R01 AI169724NIAID NIH HHS R21 AI140510NIAID NIH HHS R21 AI147573NIGMS NIH HHS R01 GM137143
6 · The paper itself

Abstract

P66, a bifunctional integral outer membrane protein, is necessary for

Indexed as

BorreliaBorrelia burgdorferiBorrelia burgdorferi GroupLyme DiseaseAmino AcidsAnimalsBacterial ProteinsEpitopesIntegrinsMammalsMicePorinsAmino AcidsBacterial ProteinsEpitopesIntegrinsPorinsbacterial pathogenesisBorrelia burgdorferic-Myc epitope taginfectious diseaseLyme diseaseP66

Identifiers

PMID36211976
PMCPMC9539438
OpenAlexW4296828728

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.