Evidence map›Paper›PMID 36211488›Full record

ArticleFrontiers in nutrition2022

Modulation of gut microbiota: The effects of a fruits and vegetables supplement.

Arun Prasath Lakshmanan, Alessandra Mingione, Francesca Pivari, Elena Dogliotti, Caterina Brasacchio, Selvasankar Murugesan, Daniele Cusi, Monica Lazzaroni, Laura Soldati, Annalisa Terranegra

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Fruit-Based Diet and Gut Health: A Review.Food science & nutrition · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Arun Prasath LakshmananPrecision Nutrition, Research Department, Sidra Medicine, Doha, Qatar.
Alessandra MingioneDepartment of Biomedical and Clinical Sciences L. Sacco, University of Milan, Milan, Italy.
Francesca PivariDepartment of Health Sciences, University of Milan, Milan, Italy.
Elena DogliottiFondazione Umberto Veronesi, Milan, Italy.
Caterina BrasacchioDepartment of Health Sciences, University of Milan, Milan, Italy.
Selvasankar MurugesanMicrobiome and Host-Microbes Interactions Lab, Research Department, Sidra Medicine, Doha, Qatar.
Daniele CusiInstitute of Biomedical Technologies, Italian National Research Council, Milan, Italy.
Monica LazzaroniLaboratory of Clinical Pathology, Foundation IRCCS Neurological Institute C. Besta, Milan, Italy.
Laura SoldatiDepartment of Health Sciences, University of Milan, Milan, Italy.
Annalisa TerranegraPrecision Nutrition, Research Department, Sidra Medicine, Doha, Qatar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The consumption of an optimal amount of fruits and vegetables is known to improve physical fitness and physiological body functions. Healthy eating habits, including intake of fruits and vegetables, can modify gut microbiota. This study aimed to demonstrate the effectiveness of a formulated fruit and vegetable supplement (FVS) in modulating the antioxidant capacity and the gut microbiota composition. We enrolled 30 healthy volunteer subjects, matched for age, gender, BMI, and smoking habits, and randomized them into the FVS and the placebo (PLA) groups. Among the serum vitamins, the folic acid level was significantly higher (

Indexed as

antioxidant capacitydiet supplementsfruits and vegetablesgut microbiotaSCFA

Identifiers

PMID36211488
PMCPMC9537686

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.