Evidence map›Paper›PMID 36211472›Full record

ArticleFrontiers in cell and developmental biology2022

Mild cold stress specifically disturbs clustering movement of DFCs and sequential organ left-right patterning in zebrafish.

Min Liu, Xinyu Zou, Mao Fu, Xinping Bai, Yongyan Zhao, Xin Chen, Xiaoyu Wang, Peijian Wang, Sizhou Huang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Min LiuDevelopment and Regeneration Key Laboratory of Sichuan Province, Department of Anatomy and Histology and Embryology, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, China.
Xinyu ZouSchool of Pharmacy, Chengdu Medical College, Chengdu, China.
Mao FuSchool of Pharmacy, Chengdu Medical College, Chengdu, China.
Xinping BaiSchool of Clinical Medicine, Chengdu Medical College, Chengdu, China.
Yongyan ZhaoSchool of Clinical Medicine, Chengdu Medical College, Chengdu, China.
Xin ChenSchool of Public Health, Chengdu Medical College, Chengdu, China.
Xiaoyu WangSchool of Biomedical Sciences, Chengdu Medical College, Chengdu, China.
Peijian WangDepartment of Cardiology, the First Affiliated Hospital, Chengdu Medical College, Chengdu, China.
Sizhou HuangDevelopment and Regeneration Key Laboratory of Sichuan Province, Department of Anatomy and Histology and Embryology, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, China.
Chengdu Medical College · CNFirst Affiliated Hospital of Chengdu Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In poikilothermic animals, the distinct acclimatization ability of different organs has been previously addressed, while the tissue-specific role of cold stress in early development is largely unknown. In this study, we discovered that despite its role in delaying embryonic development, mild cold stress (22°C) does not disturb multiple-organ progenitor specification, but does give rise to organ left-right (LR) patterning defects. Regarding the mechanism, the data showed that mild cold stress downregulated the expression of cell-adhesion genes

Indexed as

Cdh1Cdh2cold stressDFCsLR patterning defectzebrafish

Identifiers

PMID36211472
PMCPMC9539758
OpenAlexW4296826592

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.