Evidence map›Paper›PMID 36211440›Full record

ArticleFrontiers in immunology2022

Complement activation in Hidradenitis suppurativa: Covert low-grade inflammation or innocent bystander?

K R van Straalen, K Dudink, P Aarts, H H van der Zee, T P P van den Bosch, J Giang, E P Prens, J Damman

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

K R van StraalenDepartment of Dermatology, University of Michigan Medical School, Ann Arbor, MI, United States.
K DudinkDepartment of Dermatology, Erasmus University Medical Center Rotterdam, Rotterdam, Netherlands.
P AartsDepartment of Dermatology, Erasmus University Medical Center Rotterdam, Rotterdam, Netherlands.
H H van der ZeeDepartment of Dermatology, Erasmus University Medical Center Rotterdam, Rotterdam, Netherlands.
T P P van den BoschDepartment of Pathology, Erasmus University Medical Center Rotterdam, Rotterdam, Netherlands.
J GiangDepartment of Pathology, Maasstad Hospital, Rotterdam, Netherlands.
E P PrensDepartment of Dermatology, Erasmus University Medical Center Rotterdam, Rotterdam, Netherlands.
J DammanDepartment of Pathology, Erasmus University Medical Center Rotterdam, Rotterdam, Netherlands.
Erasmus MC · NLMaasstad Ziekenhuis · NLUniversity of Michigan–Ann Arbor · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hidradenitis suppurativa (HS) is a chronic auto-inflammatory skin disease with a complex and multifactorial pathogenesis involving both the innate and adaptive immune system. Despite limited evidence for

Indexed as

Hidradenitis SuppurativaComplement ActivationComplement C1qComplement Membrane Attack ComplexHumansInflammationProperdinReceptor, Anaphylatoxin C5aComplement C1qComplement Membrane Attack ComplexProperdinReceptor, Anaphylatoxin C5abacteriaC5a anaphylatoxincomplement -innate immune systemhidradenitis suppurativaimmune systemtreatment

Identifiers

PMID36211440
PMCPMC9535337
OpenAlexW4296633641

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.