Evidence map›Paper›PMID 36211404›Full record

ArticleFrontiers in immunology2022

Reaction of SARS-CoV-2 antibodies with other pathogens, vaccines, and food antigens.

Aristo Vojdani, Elroy Vojdani, Ashley L Melgar, Joshua Redd

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Aristo VojdaniImmunosciences Lab, Los Angeles, CA, United States.
Elroy VojdaniRegenera Medical, Los Angeles, CA, United States.
Ashley L MelgarBiological Sciences, UC Irvine, Irvine, CA, United States.
Joshua ReddRedRiver Health and Wellness, South Jordan, UT, United States.
Immunosciences Lab (United States) · USRegeneris Medical · USUC Irvine Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been shown that SARS-CoV-2 shares homology and cross-reacts with vaccines, other viruses, common bacteria and many human tissues. We were inspired by these findings, firstly, to investigate the reaction of SARS-CoV-2 monoclonal antibody with different pathogens and vaccines, particularly DTaP. Additionally, since our earlier studies have shown immune reactivity by antibodies made against pathogens and autoantigens towards different food antigens, we also studied cross-reaction between SARS-CoV-2 and common foods. For this, we reacted monoclonal and polyclonal antibodies against SARS-CoV-2 spike protein and nucleoprotein with 15 different bacterial and viral antigens and 2 different vaccines, BCG and DTaP, as well as with 180 different food peptides and proteins. The strongest reaction by SARS-CoV-2 antibodies were with DTaP vaccine antigen,

Indexed as

ChitinasesCOVID-19Diphtheria-Tetanus-acellular Pertussis VaccinesAntibodies, MonoclonalAntibodies, ViralAntigens, ViralAutoantigensBCG VaccineBromelainsCaseinsHepatitis B e AntigensHumansNucleoproteinsSARS-CoV-2Spike Glycoprotein, CoronavirusAntibodies, MonoclonalAntibodies, ViralAntigens, ViralAutoantigensBCG VaccineBromelainsCaseinsChitinasesDiphtheria-Tetanus-acellular Pertussis VaccinesHepatitis B e AntigensNucleoproteinsSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2antibodiesfood antigensmolecular mimicrypathogensSARS-CoV-2vaccines

Identifiers

PMID36211404
PMCPMC9537454
OpenAlexW4297004622

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.