Evidence map›Paper›PMID 36211394›Full record

ArticleFrontiers in immunology2022

Genetic analysis of CFH and MCP in Egyptian patients with immune-complex proliferative glomerulonephritis.

Heba R Gouda, Iman M Talaat, Amal Bouzid, Hoda El-Assi, Amira Nabil, Thenmozhi Venkatachalam, Poorna Manasa Bhamidimarri, Inken Wohlers, Amena Mahdami, Saba El-Gendi and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Microbial dysbiosis and inferred functional profiling reveals the potential role ofFrontiers in cellular and infection microbiology · 2026
    Article
  5. Article
  6. Article
  7. Association of specificFrontiers in immunology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 4 countries.

Heba R GoudaPathology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Iman M TalaatPathology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Amal BouzidSharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab Emirates.
Hoda El-AssiHuman Genetics Unit, Pathology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Amira NabilHuman Genetics Department, Medical Research Institute, Alexandria University, Alexandria, Egypt.
Thenmozhi VenkatachalamDepartment of Physiology and Immunology, College of Medicine, Khalifa University, Abu Dhabi, United Arab Emirates.
Poorna Manasa BhamidimarriSharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab Emirates.
Inken WohlersMedical Systems Biology Division, Lübeck Institute of Experimental Dermatology and Institute for Cardiogenetics, University of Lübeck, Lübeck, Germany.
Amena MahdamiSharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab Emirates.
Saba El-GendiPathology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Ahmed ElKoraieNephrology Unit, Internal Medicine Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Hauke BuschMedical Systems Biology Division, Lübeck Institute of Experimental Dermatology and Institute for Cardiogenetics, University of Lübeck, Lübeck, Germany.
Maha Saber-AyadClinical Sciences Department, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates.
Rifat HamoudiClinical Sciences Department, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates.
Nahed BaddourPathology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Alexandria University · EGUniversity of Sharjah · AEUniversity of Lübeck · DECairo University · EGKhalifa University of Science and Technology · AEUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glomerulonephritis (GN) is a complex disease with intricate underlying pathogenic mechanisms. The possible role of underlying complement dysregulation is not fully elucidated in some GN subsets, especially in the setting of autoimmunity or infection. In the current study, diagnosed cases of lupus nephritis (LN) and post-infectious GN (PIGN) were recruited for molecular genetic analysis and targeted next-generation DNA sequencing was performed for two main complement regulating genes: in the fluid phase;

Indexed as

GlomerulonephritisLupus NephritisComplement Factor HComplement System ProteinsEgyptHeterozygoteHumansMembrane Cofactor ProteinCD46 protein, humanCFH protein, humanComplement Factor HComplement System ProteinsMembrane Cofactor ProteinCFHcomplement systemglomerulonephritislupus nephritisMCPpost-infectious glomerulonephritis

Identifiers

PMID36211394
PMCPMC9539770
OpenAlexW4296896695

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.