Evidence map›Paper›PMID 36211337›Full record

ArticleFrontiers in immunology2022

Highly different effects of phage therapy and antibiotic therapy on immunological responses of chickens infected with

Łukasz Grabowski, Grzegorz Węgrzyn, Alicja Węgrzyn, Magdalena Podlacha

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Bacteriophages targetingFrontiers in microbiology · 2026
    Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Phage-Based Biosanitation Strategies for Minimizing PersistentAnimals : an open access journal from MDPI · 2023
    Review
  16. Modulation of Caecal Microbiota and Metabolome Profile inInternational journal of molecular sciences · 2023
    Article
  17. Article
  18. Review
  19. Phage Therapy vs. the Use of Antibiotics in the Treatment ofAntibiotics (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Łukasz GrabowskiLaboratory of Phage Therapy, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Gdansk, Poland.
Grzegorz WęgrzynDepartment of Molecular Biology, Faculty of Biology, University of Gdansk, Gdansk, Poland.
Alicja WęgrzynLaboratory of Phage Therapy, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Gdansk, Poland.
Magdalena PodlachaDepartment of Molecular Biology, Faculty of Biology, University of Gdansk, Gdansk, Poland.
Institute of Biochemistry and Biophysics, Polish Academy of Sciences · PLUniversity of Gdańsk · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The appearance of bacteria resistant to most or even all known antibiotics has become a serious medical problem. One such promising and effective alternative form of therapy may be the use of phages, the administration of which is considered to be safe and highly effective, especially in animals with drug-resistant infections. Although there have been no reports to date suggesting that bacteriophages can cause any severe complications or adverse effects, we still know little about their interactions with animal organisms, especially in the context of the functioning of the immune system. Therefore, the aim of the present study was to compare the impact of the application of selected bacteriophages and antibiotics (enrofloxacin and colistin), commonly used in veterinary medicine, on immune functions in

Indexed as

BacteriophagesPhage TherapyAnimalsAnti-Bacterial AgentsChickensColistinCorticosteroneCytokinesEnrofloxacinHydrocortisoneInterleukin-10Interleukin-12Interleukin-4Interleukin-6Interleukin-8Salmonella typhimuriumAnti-Bacterial AgentsColistinCorticosteroneCytokinesEnrofloxacinHydrocortisoneInterleukin-10Interleukin-12Interleukin-4Interleukin-6Interleukin-8chicken immunitycytokinesphage therapysafety and efficacySalmonella enterica infectionstress hormones

Identifiers

PMID36211337
PMCPMC9539762
OpenAlexW4296839827

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.