ArticleFrontiers in surgery2022
Hounsfield unit for assessing asymmetrical loss of vertebral bone mineral density and its correlation with curve severity in adolescent idiopathic scoliosis.
Article in Frontiers in surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Association between LIV + 1 bone mineral density asymmetry and distal adding-on phenomenon in adolescent idiopathic scoliosis.Journal of orthopaedic surgery and research · 2026Article
- Opportunistic bone mineral density assessment in pediatric scoliosis: validating Hounsfield unit measurement from lumbar CT images.Spine deformity · 2026Article
- Pathogenic mechanisms of adult degenerative scoliosis.Frontiers in cell and developmental biology · 2026Review
- The impact of osteoporosis on spinal biomechanical stability in adolescent idiopathic scoliosis: a narrative review of finite element analysis and bone mineral density assessment.Frontiers in bioengineering and biotechnology · 2026Review
- Vertebral bone density variation and site-specific computed tomography measurements for risk of subsequent fracture post-cement augmentation: a retrospective study.Quantitative imaging in medicine and surgery · 2025Article
- The relationship between postoperative proximal junctional kyphosis and MRI-based pedicle bone quality scores in thoracic adolescent idiopathic scoliosis.BMC surgery · 2025Article
- Results of bracing adolescent idiopathic scoliosis in the context of clinical practice and the Scoliosis Research Society's criteria: 5-year observational study from a German orthopaedic university hospital.European journal of medical research · 2024Observational
- Asymmetric Osteopenia in Adolescent Idiopathic Scoliosis Based on Hounsfield Unit of Computed Tomography.International journal of general medicine · 2024Article
- The role of lumbosacral paraspinal muscle degeneration and low vertebral bone mineral density on distal instrumentation-related problems following long-instrumented spinal fusion for degenerative lumbar scoliosis: a retrospective cohort study.Quantitative imaging in medicine and surgery · 2023Article
- Reduced Volumetric Bone Mineral Density of the Spine in Adolescent Rett Girls with Scoliosis.Children (Basel, Switzerland) · 2022Article
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6 authors.
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Abstract
Background: Low bone mass concomitantly occurs in patients with adolescent idiopathic scoliosis (AIS) and can persist until skeletal maturity. The purpose of this study was to assess the asymmetrical loss of vertebral bone mineral density (vBMD) and its correlation with curve severity in patients with AIS using Hounsfield unit (HU) values measured from computed tomography scans. Methods: A total of 93 AIS patients were retrospectively recruited. The HU values of the vertebral body (VB-HU) and pedicle screw trajectory (PST-HU) were measured from four vertebrae above (Apex - 4) to four below (Apex + 4) the apical vertebra (Apex) of the major curve. The VB-HU and PST-HU at the upper end vertebra, Apex, and lower end vertebra within the concave and convex sides of the major and minor curves and stable vertebrae were obtained. Results: A significant correlation was found between the Cobb angle and VB-HU at the periapical levels of the major curve. VB-HU and PST-HU at periapical levels were significantly greater within the concavity than the convexity of both major and minor curves. The asymmetric ratios of VB-HU and PST-HU were significantly correlated with the major curve Cobb angle, peaked at the apex, and gradually diminished from the apex to the end vertebrae. The asymmetrical loss of vBMD aggravated with the progression of curve severity, presenting as VB-HU, significantly decreased within the convexity and insignificantly decreased within the concavity of the major curve. Conclusion: The asymmetrical loss of vBMD was associated with the progression of curve severity in AIS. For patients with severe AIS, the distraction of the pedicle screws at the concave side should be a priority in correcting the major curve, and supplemental anchors and larger-sized screws should be placed within the convex side around the apex of the major curve to reduce the risk of screw loosening after surgery.
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