Evidence map›Paper›PMID 36211217›Full record

ArticleCanadian journal of veterinary research = Revue canadienne de recherche veterinaire2022

Relationship of persistent lymphocytosis, antibody titers, and proviral load with expression of interleukin-12, interferon-γ, interleukin-2, interleukin-4, interleukin-10, and transforming growth factor-β in cows infected with bovine leukemia virus from a high-prevalence dairy complex.

Ernesto Marin-Flamand, Diana Michele Araiza-Hernandez, Alejandro Vargas-Ruiz, Ignacio Carlos Rangel-Rodríguez, Lilia A González-Tapia, Hugo Ramírez-Álvarez, Ruperto Javier Hernández-Balderas, Lucía Angélica García-Camacho

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. A Comprehensive Review of the Bovine Immune Response to Pathogens.International journal of molecular sciences · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ernesto Marin-FlamandDepartment of Biological Sciences, College of Superior Studies, National University of Mexico, Cuautitlán-Teoloyucan km 2.5, 54714 Cuautitlán Izcalli, Mexico City, Mexico.
Diana Michele Araiza-HernandezDepartment of Biological Sciences, College of Superior Studies, National University of Mexico, Cuautitlán-Teoloyucan km 2.5, 54714 Cuautitlán Izcalli, Mexico City, Mexico.
Alejandro Vargas-RuizDepartment of Biological Sciences, College of Superior Studies, National University of Mexico, Cuautitlán-Teoloyucan km 2.5, 54714 Cuautitlán Izcalli, Mexico City, Mexico.
Ignacio Carlos Rangel-RodríguezDepartment of Biological Sciences, College of Superior Studies, National University of Mexico, Cuautitlán-Teoloyucan km 2.5, 54714 Cuautitlán Izcalli, Mexico City, Mexico.
Lilia A González-TapiaDepartment of Biological Sciences, College of Superior Studies, National University of Mexico, Cuautitlán-Teoloyucan km 2.5, 54714 Cuautitlán Izcalli, Mexico City, Mexico.
Hugo Ramírez-ÁlvarezDepartment of Biological Sciences, College of Superior Studies, National University of Mexico, Cuautitlán-Teoloyucan km 2.5, 54714 Cuautitlán Izcalli, Mexico City, Mexico.
Ruperto Javier Hernández-BalderasDepartment of Biological Sciences, College of Superior Studies, National University of Mexico, Cuautitlán-Teoloyucan km 2.5, 54714 Cuautitlán Izcalli, Mexico City, Mexico.
Lucía Angélica García-CamachoDepartment of Biological Sciences, College of Superior Studies, National University of Mexico, Cuautitlán-Teoloyucan km 2.5, 54714 Cuautitlán Izcalli, Mexico City, Mexico.
Universidad de Cuautitlán Izcalli · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bovine leukemia virus (BLV) subclinical infection promotes persistent lymphocytosis (PL), which is related to susceptibility and progression to lymphoma. Moreover, lymphocyte counts directly correlate with BLV antibody titers and proviral load, and cell immune responses are considered atypical due to immune suppression. In order to determine the relationship of PL, antibody titers, and proviral load with interleukin (IL)-12, interferon (IFN)-γ, IL-2, IL-4, IL-10, and transforming growth factor (TGF)-β expression in a 3-month interval, 58 cows were selected (30 BLV

Indexed as

Cattle DiseasesEnzootic Bovine LeukosisLeukemia Virus, BovineLymphocytosisAnimalsCattleCytokinesFemaleInterferon-gammaInterleukin-10Interleukin-12Interleukin-2Interleukin-4PrevalenceProvirusesTransforming Growth Factor betaCytokinesInterferon-gammaInterleukin-10Interleukin-12Interleukin-2Interleukin-4Transforming Growth Factor betaTransforming Growth Factors

Identifiers

PMID36211217
PMCPMC9536356
OpenAlexW4304117653

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.