Evidence map›Paper›PMID 36211053›Full record

ArticleACS omega2022

Addition of Lauryldimethylamine

Leslie Bautista, Lucy Pill-Pepe, Neeraj Kapoor, Scott Snyder, Ellen Chu, Paresh Agarwal, Mohammed Sardar, Shylaja Arulkumar, Aym Berges, Mark Iverson and 3 more

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Leslie BautistaVaxcyte, Inc., 825 Industrial Road, Suite 300, San Carlos, California 94070, United States.ORCID https://orcid.org/0000-0002-4275-8069
Lucy Pill-PepeVaxcyte, Inc., 825 Industrial Road, Suite 300, San Carlos, California 94070, United States.
Neeraj KapoorVaxcyte, Inc., 825 Industrial Road, Suite 300, San Carlos, California 94070, United States.ORCID https://orcid.org/0000-0001-7888-6452
Scott SnyderVaxcyte, Inc., 825 Industrial Road, Suite 300, San Carlos, California 94070, United States.
Ellen ChuVaxcyte, Inc., 825 Industrial Road, Suite 300, San Carlos, California 94070, United States.
Paresh AgarwalVaxcyte, Inc., 825 Industrial Road, Suite 300, San Carlos, California 94070, United States.
Mohammed SardarVaxcyte, Inc., 825 Industrial Road, Suite 300, San Carlos, California 94070, United States.
Shylaja ArulkumarVaxcyte, Inc., 825 Industrial Road, Suite 300, San Carlos, California 94070, United States.
Aym BergesVaxcyte, Inc., 825 Industrial Road, Suite 300, San Carlos, California 94070, United States.
Mark IversonVaxcyte, Inc., 825 Industrial Road, Suite 300, San Carlos, California 94070, United States.
Christopher BehrensVaxcyte, Inc., 825 Industrial Road, Suite 300, San Carlos, California 94070, United States.
Olivier MarcqVaxcyte, Inc., 825 Industrial Road, Suite 300, San Carlos, California 94070, United States.
Jeff FairmanVaxcyte, Inc., 825 Industrial Road, Suite 300, San Carlos, California 94070, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Strain-promoted azide-alkyne cycloaddition (SPAAC) reactions like click chemistry have the potential to be highly scalable, robust, and cost-effective methods for generating small- and large-molecule conjugates for a variety of applications. However, despite method improvements, the rates of copper-based click chemistry reactions continue to be much faster than the rates of copper-free click chemistry reactions, which makes broader deployment of click chemistry challenging from a safety and compatibility standpoint. In this study, we used a zwitterionic detergent, namely, lauryldimethylamine

Identifiers

PMID36211053
PMCPMC9535640
OpenAlexW4296481710

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.