Evidence map›Paper›PMID 36210748›Full record

ReviewJournal of biosciences2022

Metastasis-associated protein 1: A potential driver and regulator of the hallmarks of cancer.

Chaitanya Vattem, Suresh B Pakala

Abstract readReview
PubMed
In one paragraph

Review in Journal of biosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Prenatal black carbon exposure and DNA methylation in umbilical cord blood.International journal of hygiene and environmental health · 2025
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Chaitanya VattemBiology Division, Indian Institute of Science Education and Research (IISER) Tirupati,Tirupati 517 507, India.
Suresh B Pakala
Indian Institute of Science Education and Research, Tirupati · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metastasis-associated protein 1 (MTA1) is an emerging transcriptional co-regulator and was found to be aberrantly expressed in different types of cancers. MTA1 has been reported to regulate multiple cancer-related signalling pathways leading to tumour progression and metastasis. Recently, MTA1 was also implicated in cancer metabolism, where it was found to regulate the 'Warburg effect' to drive breast cancer cell invasion. Overall, the functional dynamism of MTA1 can be attributed to its dual co-regulatory effects in regulating a diverse array of target genes involved in cell proliferation, DNA damage repair, angiogenesis, invasion, migration, metastasis, and metabolism in different types of cancers. In this review, we have attempted to provide a brief summary of MTA1 as a modulator of the hallmarks of cancer.

Indexed as

Histone DeacetylasesNeoplasmsCell Line, TumorCell ProliferationGene Expression Regulation, NeoplasticHumansRepressor ProteinsTrans-ActivatorsHistone DeacetylasesMTA1 protein, humanRepressor ProteinsTrans-Activators

Identifiers

PMID36210748
OpenAlexW4223983650

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.