Evidence map›Paper›PMID 36210564›Full record

ArticleThrombosis research2022

COVID-19 associated coagulopathy and thrombosis in cancer.

Marcel Levi, Nick van Es

Open access · hybridAbstract read
In one paragraph

Article in Thrombosis research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Marcel LeviDepartment of Vascular Medicine, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centre, Amsterdam, the Netherlands; Department of Medicine, University College London Hospitals NHS Foundation Trust, London, United Kingdom; Cardiometabolic Programme-NIHR UCLH/UCL BRC, London, United Kingdom. Electronic address: m.m.levi@amsterdamumc.nl.
Nick van EsDepartment of Vascular Medicine, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centre, Amsterdam, the Netherlands.
Amsterdam University Medical Centers · NLUCL Biomedical Research Centre · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer patients are at risk for a more severe COVID-19 infection as well as an adverse outcome of such infection. This may be caused by the cancer itself (e.g haematological malignancies and lung cancer) or due to immune suppression caused by anti-cancer treatment. Severe COVID-19 infections are often complicated by a coagulopathy that clinically results in a high incidence of venous thromboembolic disease. Cancer itself is associated with a hypercoagulable state and a markedly increased incidence of thromboembolic complications, hence the combination of cancer and COVID-19 may amplify this risk. COVID-19 vaccination seems safe and effective in most cancer patients although adapted and bespoke vaccination schemes may increase the seroconversion rate and immune response in selected patients. Specific management strategies to improve outcomes of cancer patients in COVID-19 (e.g. higher intensity antithrombotic prophylaxis) are lacking and should be evaluated in clinical studies simultaneously focusing on efficacy and safety.

Indexed as

Blood Coagulation DisordersCOVID-19NeoplasmsThromboembolismThrombosisAnticoagulantsCOVID-19 VaccinesFibrin Fibrinogen Degradation ProductsFibrinolytic AgentsHumansSARS-CoV-2AnticoagulantsCOVID-19 VaccinesFibrin Fibrinogen Degradation ProductsFibrinolytic AgentsCoagulationCOVID-19D-dimerDisseminated intravascular coagulationPulmonary embolismSARS-CoV-2ThrombosisThrombotic microangiopathy

Identifiers

PMID36210564
PMCPMC9134033
OpenAlexW4281551869

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.