Evidence map›Paper›PMID 36210437›Full record

ArticleBMC medicine2022

Hesitancy for receiving regular SARS-CoV-2 vaccination in UK healthcare workers: a cross-sectional analysis from the UK-REACH study.

Neyme Veli, Christopher A Martin, Katherine Woolf, Joshua Nazareth, Daniel Pan, Amani Al-Oraibi, Rebecca F Baggaley, Luke Bryant, Laura B Nellums, Laura J Gray and 3 more

Open access · goldAbstract read
In one paragraph

Article in BMC medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Neyme Veli *Department of Respiratory Sciences, University of Leicester, Leicester, UK.
Christopher A Martin *Department of Respiratory Sciences, University of Leicester, Leicester, UK.
Katherine WoolfUniversity College London Medical School, London, UK.
Joshua NazarethDepartment of Respiratory Sciences, University of Leicester, Leicester, UK.
Daniel PanDepartment of Respiratory Sciences, University of Leicester, Leicester, UK.
Amani Al-OraibiDepartment of Respiratory Sciences, University of Leicester, Leicester, UK.
Rebecca F BaggaleyDepartment of Respiratory Sciences, University of Leicester, Leicester, UK.
Luke BryantDepartment of Respiratory Sciences, University of Leicester, Leicester, UK.
Laura B NellumsPopulation and Lifespan Sciences, School of Medicine, University of Nottingham, Nottingham, UK.
Laura J GrayBiostatistics Research Group, Department of Health Sciences, University of Leicester, Leicester, UK.
Kamlesh KhuntiDiabetes Research Centre, University of Leicester, Leicester, UK.
Manish PareekDepartment of Respiratory Sciences, University of Leicester, Leicester, UK. mp426@le.ac.uk.ORCID 0000-0003-1521-9964
UK-REACH Study Collaborative Group
University of Leicester · GBUniversity College London · GBUniversity of Nottingham · GB

Funding

Department of HealthMedical Research Council MR/V027549/1
6 · The paper itself

Abstract

backgroundRegular vaccination against SARS-CoV-2 may be needed to maintain immunity in 'at-risk' populations, which include healthcare workers (HCWs). However, little is known about the proportion of HCWs who might be hesitant about receiving a hypothetical regular SARS-CoV-2 vaccination or the factors associated with this hesitancy.

methodsCross-sectional analysis of questionnaire data collected as part of UK-REACH, a nationwide, longitudinal cohort study of HCWs. The outcome measure was binary, either a participant indicated they would definitely accept regular SARS-CoV-2 vaccination if recommended or they indicated some degree of hesitancy regarding acceptance (probably accept or less likely). We used logistic regression to identify factors associated with hesitancy for receiving regular vaccination.

resultsA total of 5454 HCWs were included in the analysed cohort, 23.5% of whom were hesitant about regular SARS-CoV-2 vaccination. Black HCWs were more likely to be hesitant than White HCWs (aOR 2.60, 95%CI 1.80-3.72) as were those who reported a previous episode of COVID-19 (1.33, 1.13-1.57 [vs those who tested negative]). Those who received influenza vaccination in the previous two seasons were over five times less likely to report hesitancy for regular SARS-CoV-2 vaccination than those not vaccinated against influenza in either season (0.18, 0.14-0.21). HCWs who trusted official sources of vaccine information (such as NHS or government adverts or websites) were less likely to report hesitancy for a regular vaccination programme. Those who had been exposed to information advocating against vaccination from friends and family were more likely to be hesitant.

conclusionsIn this study, nearly a quarter of UK HCWs were hesitant about receiving a regular SARS-CoV-2 vaccination. We have identified key factors associated with hesitancy for regular SARS-CoV-2 vaccination, which can be used to identify groups of HCWs at the highest risk of vaccine hesitancy and tailor interventions accordingly. Family and friends of HCWs may influence decisions about regular vaccination. This implies that working with HCWs and their social networks to allay concerns about SARS-CoV-2 vaccination could improve uptake in a regular vaccination programme.

trial registrationISRCTN Registry, ISRCTN11811602.

Indexed as

COVID-19Influenza, HumanCOVID-19 VaccinesCross-Sectional StudiesHealth PersonnelHumansLongitudinal StudiesSARS-CoV-2United KingdomVaccinationCOVID-19 VaccinesCOVID-19EthnicityHealthcareHesitancySARS-CoV-2Vaccination

Identifiers

PMID36210437
PMCPMC9548389
OpenAlexW4303945564

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.