Evidence map›Paper›PMID 36210425›Full record

ArticleBulletin of experimental biology and medicine2022

Differences in Gut Microbiota Composition and Predicted Metabolic Functions: a Pilot Study of Adolescents with Normal Weight and Obesity.

E S Klimenko, N L Belkova, A I Romanitsa, A V Pogodina, L V Rychkova, M A Darenskaya

Abstract read
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In one paragraph

Article in Bulletin of experimental biology and medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Gut Microbiome Interactions with Oxidative Stress: Mechanisms and Consequences for Health.Pathophysiology : the official journal of the International Society for Pathophysiology · 2024
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

E S KlimenkoScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia. klimenko.elizabet@gmail.com.
N L BelkovaScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.
A I RomanitsaScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.
A V PogodinaScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.
L V RychkovaScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.
M A DarenskayaScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.
Scientific Center of Family Health Problems and Human Reproduction · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the principles underlying the stability and sustainability of the gut microbiome of adolescents with normal weight and obesity will make it possible to implement a personalized approach to the correction of metabolic disorders. The article presents the results of a pilot study of the diversity and metabolic potential of the gut microbiome in adolescents with normal body weight and obesity. Biological material was studied using metagenomic sequencing of the V3-V4 variable regions of the 16S rRNA gene. In all adolescents with normal weight, similar degree of the phylogenetic relationship between the bacterial taxa of the community was demonstrated. In contrast, obese adolescents were characterized by the presence of phylogenetically distinct taxa in the gut microbiota. However, even with differences in taxonomic composition, the gut microbial community can compensate for the absence of certain taxonomic groups by implementing the necessary metabolic functions using other phylogenetically close taxa.

Indexed as

Gastrointestinal MicrobiomeAdolescentFecesHumansObesityPhylogenyPilot ProjectsRNA, Ribosomal, 16SRNA, Ribosomal, 16Sadolescentscomposition and structure of the microbial communitygut microbiotametabolic potentialobesity

Identifiers

PMID36210425
OpenAlexW4303983120

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.