Evidence map›Paper›PMID 36210413›Full record

ArticleBulletin of experimental biology and medicine2022

Changes in Spermatogenesis, Lipoperoxidation Processes, and Antioxidant Protection in Men with Pathozoospermia after COVID-19. The Effectiveness of Correction with a Promising Antioxidant Complex.

N A Kurashova, B G Dashiev, S I Kolesnikov, P S Dmitrenok, E P Kozlovskaya, S P Kasyanov, N V Epur, V G Usov, L I Kolesnikova

Open access · bronzeAbstract read
In one paragraph

Article in Bulletin of experimental biology and medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Carotenoids from StarfishMarine drugs · 2023
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

N A KurashovaScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia. nakurashova@yandex.ru.
B G DashievScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.
S I KolesnikovScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.
P S DmitrenokG. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far East Division of the Russian Academy of Sciences, Vladivostok, Russia.
E P KozlovskayaG. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far East Division of the Russian Academy of Sciences, Vladivostok, Russia.
S P KasyanovA. V. Zhirmunsky National Scientific Center of Marine Biology, Far East Division of the Russian Academy of Sciences, Vladivostok, Russia.
N V EpurA. V. Zhirmunsky National Scientific Center of Marine Biology, Far East Division of the Russian Academy of Sciences, Vladivostok, Russia.
V G UsovA. V. Zhirmunsky National Scientific Center of Marine Biology, Far East Division of the Russian Academy of Sciences, Vladivostok, Russia.
L I KolesnikovaScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.
Scientific Center of Family Health Problems and Human Reproduction · RUA.V. Zhirmunsky National Scientific Center of Marine Biology Far Eastern Branch of the Russian Academy of Sciences · RUPacific Institute of Bioorganic Chemistry. GB Elyakova Far Eastern Branch of the Russian Academy of Sciences · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The indicators of spermatogenesis and the state of LPO and antioxidant protection in men with pathozoospermia after COVID-19 were assessed before and after treatment an antioxidant complex. Blood plasma served as the material for biochemical studies. In the examined patients, the parameters of spermatogenesis, as well as blood concentration of LPO components (diene conjugates and TBA-reactive substances) were analyzed. The total antioxidant activity of the blood was determined as an indicator characterizing the total activity of LPO inhibitors and determining its buffer capacity. In patients recovered from COVID-19, an increase in spermatogenesis disorders and shifts towards the predominance of prooxidant factors were observed. After a course (1 month) of antioxidant complex, patients showed increased sperm motility, decreased leukocyte count in the ejaculate, and restored balance in the prooxidant-antioxidant system towards antioxidant components. The effectiveness of correction of post-COVID disorders largely depends on the degree of damage to the structure and function of cell membranes caused by oxidative stress. The use of the antioxidant complex is a promising option, because it reduces the level of LPO, enhances antioxidant protection of the body, and also normalizes some parameters of spermatogenesis.

Indexed as

AntioxidantsCOVID-19 Drug TreatmentHumansLipid PeroxidationMaleOxidative StressReactive Oxygen SpeciesSpermatogenesisSperm MotilityAntioxidantsReactive Oxygen SpeciesastaxanthinCOVID-19omega-3 fatty acidsoxidative stressspermatogenesis

Identifiers

PMID36210413
PMCPMC9548424
OpenAlexW4303983420

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.