ArticleBiochemical and biophysical research communications2022
Fluid shear stress enhances proliferation of breast cancer cells via downregulation of the c-subunit of the F
Article in Biochemical and biophysical research communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- ATP5F1B promotes breast cancer progression through ERK associated metabolic reprogramming.Molecular biology reports · 2026Article
- Mitophagy and Ubiquitination Coordinate Context-Specific Mitochondrial Quality Control and EMT/MET Plasticity to Drive Cancer Cell Invasion.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Model Circulating Tumor Cells Induced by Mechanical Stress.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Maternal nitrate supplementation improves offspring cardiometabolic outcomes in obese pregnancies.Annals of medicine · 2025Article
- The impact of compression and confinement in tumor growth and progression: emerging concepts in cancer mechanobiology.Frontiers in materials · 2025Article
- Mechanical shear flow regulates the malignancy of colorectal cancer cells.The Kaohsiung journal of medical sciences · 2024Article
- Loss of Hormone Receptor Expression after Exposure to Fluid Shear Stress in Breast Cancer Cell Lines.International journal of molecular sciences · 2024Article
- Extracellular Vesicle-Mediated Modulation of Stem-like Phenotype in Breast Cancer Cells under Fluid Shear Stress.Biomolecules · 2024Article
- Biophysical interplay between extracellular matrix remodeling and hypoxia signaling in regulating cancer metastasis.Frontiers in cell and developmental biology · 2024Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
The presence of circulating cancer cells in the bloodstream is positively correlated with metastasis. We hypothesize that fluid shear stress (FSS) occurring during circulation alters mitochondrial function, enhancing metastatic behaviors of cancer cells. MCF7 and MDA-MB-231 human breast cancer cells subjected to FSS exponentially increased proliferation. Notably, FSS-treated cells consumed more oxygen but were resistant to uncoupler-mediated ATP loss. We found that exposure to FSS downregulated the F
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Registered trials
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