Evidence map›Paper›PMID 36209209›Full record

Trial reportBMC endocrine disorders2022

Feasibility and effectiveness of self-monitoring of blood glucose among insulin-dependent patients with type 2 diabetes: open randomized control trial in three rural districts in Rwanda.

Loise Ng'ang'a, Gedeon Ngoga, Symaque Dusabeyezu, Bethany L Hedt-Gauthier, Emmanuel Harerimana, Simon Pierre Niyonsenga, Charlotte M Bavuma, Gene Bukhman, Alma J Adler, Fredrick Kateera and 1 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC endocrine disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Loise Ng'ang'aPartners In Health-Rwanda, Kigali, Rwanda. loisehaks@gmail.com.
Gedeon NgogaNon-Communicable Diseases Division, Rwanda Biomedical Centre, Kigali, Rwanda.
Symaque DusabeyezuPartners In Health-Rwanda, Kigali, Rwanda.
Bethany L Hedt-GauthierGlobal Health and Social Medicine, Harvard Medical School, Boston, MA, USA.
Emmanuel HarerimanaPartners In Health-Rwanda, Kigali, Rwanda.
Simon Pierre NiyonsengaNon-Communicable Diseases Division, Rwanda Biomedical Centre, Kigali, Rwanda.
Charlotte M BavumaKigali University Teaching Hospital, College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda.
Gene BukhmanNCD Synergies, Partners In Health, Boston, MA, USA.
Alma J AdlerDivision of Global Health Equity, Brigham and Women's Hospital, Boston, MA, USA.
Fredrick KateeraPartners In Health-Rwanda, Kigali, Rwanda.
Paul H ParkNCD Synergies, Partners In Health, Boston, MA, USA.
Brigham and Women's Hospital · USHarvard University · USPartners In Health · USRwanda Biomedical Center · RWUniversity of Kigali · RW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prevalence of type 2 diabetes in sub Saharan Africa (SSA) has been on the rise. Effective control of blood glucose is key towards reducing the risk of diabetes complications. Findings mainly from high-income countries have demonstrated the effectiveness of self-monitoring of blood-glucose (SMBG) in controlling blood glucose levels. However, there are limited studies describing the implementation of SMBG in rural SSA. This study explores the feasibility and effectiveness of implementing SMBG among patients diagnosed with insulin-dependent type 2 diabetes in rural Rwanda.

methodsParticipants were randomized into intervention (n = 42) and control (n = 38) groups. The intervention group received a glucose-meter, blood test-strips, log-book, waste management box and training on SMBG in addition to usual care. The control group continued with their usual care consisting of, routine monthly medical consultation and health education. The primary outcomes were adherence to the implementation of SMBG (testing schedule and recording data in the log-book) and change in hemoglobin A1c. Descriptive statistics and a paired t-test were used to analyze the primary outcomes.

resultsIn both the intervention and control arms, majority of the participants were female (59.5% vs 52.6%) and married (71.4% vs 73.7%). Most had at most a primary level education (83.3% vs. 89.4%) and were farmers (54.8% vs. 50.0%). Among those in the intervention group, 63.4% showed good adherence to implementing SMBG based on the number of tests recorded in the glucose meter. Only 20.3% demonstrated accurate recording of the glucose level tests in log-books. The mean difference of the HbA1C from baseline to six months post-intervention was significantly better among the intervention group -0.94% (95% CI -1.46, -0.41) compared to the control group 0.73% (95% CI -0.09, 1.54) p < 0.001.

conclusionOur study showed that among patients with insulin-dependent type 2 diabetes residing in rural Rwanda, SMBG was feasible and demonstrated positive outcomes in improving blood glucose control. However, there is need for strategies to enhance accuracy in recording blood glucose test results in the log-book.

trial registrationThe trial was registered retrospectively on the Pan African Clinical Trial Registry, on 17

Indexed as

Diabetes Mellitus, Type 1Diabetes Mellitus, Type 2Blood GlucoseBlood Glucose Self-MonitoringFeasibility StudiesFemaleGlucoseGlycated HemoglobinHumansHypoglycemic AgentsInsulinMaleRetrospective StudiesRwandaBlood GlucoseGlucoseGlycated HemoglobinHypoglycemic AgentsInsulinDiabetes MellitusFeasibilityGlycemic controlSelf-monitoring of blood glucoseSub-Saharan Africa

Identifiers

PMID36209209
PMCPMC9547423
OpenAlexW4303628489

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.