Evidence map›Paper›PMID 36209195›Full record

ArticleInsights into imaging2022

Application of deep learning reconstruction of ultra-low-dose abdominal CT in the diagnosis of renal calculi.

Xiaoxiao Zhang, Gumuyang Zhang, Lili Xu, Xin Bai, Jiahui Zhang, Min Xu, Jing Yan, Daming Zhang, Zhengyu Jin, Hao Sun

Open access · goldAbstract read
In one paragraph

Article in Insights into imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 2 countries.

Xiaoxiao Zhang *Department of Radiology, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Shuaifuyuan No.1, Wangfujing Street, Dongcheng District, Beijing, 100730, China.
Gumuyang Zhang *Department of Radiology, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Shuaifuyuan No.1, Wangfujing Street, Dongcheng District, Beijing, 100730, China.
Lili XuDepartment of Radiology, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Shuaifuyuan No.1, Wangfujing Street, Dongcheng District, Beijing, 100730, China.
Xin BaiDepartment of Radiology, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Shuaifuyuan No.1, Wangfujing Street, Dongcheng District, Beijing, 100730, China.
Jiahui ZhangDepartment of Radiology, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Shuaifuyuan No.1, Wangfujing Street, Dongcheng District, Beijing, 100730, China.
Min XuCanon Medical System (China), No.10, Jiuxianqiao North Road, Chaoyang District, Beijing, 100024, China.
Jing YanCanon Medical System (China), No.10, Jiuxianqiao North Road, Chaoyang District, Beijing, 100024, China.
Daming ZhangDepartment of Radiology, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Shuaifuyuan No.1, Wangfujing Street, Dongcheng District, Beijing, 100730, China. cadina1984@163.com.
Zhengyu JinDepartment of Radiology, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Shuaifuyuan No.1, Wangfujing Street, Dongcheng District, Beijing, 100730, China. jinzy@pumch.cn.
Hao SunDepartment of Radiology, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Shuaifuyuan No.1, Wangfujing Street, Dongcheng District, Beijing, 100730, China. sunhao_robert@126.com.ORCID http://orcid.org/0000-0002-9606-9066
Chinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

Chinese Academy of Medical Sciences innovation fund for medical sciences CIFMS 2021-I2M-C&T-B-022Clinical and Translational Research Project of Chinese Academy of Medical Sciences 2019XK320028National High Level Hospital Clinical Research Funding 2022-PUMCH-A-033National High Level Hospital Clinical Research Funding 2022-PUMCH-A-035National Natural Science Foundation of China 81901742National Natural Science Foundation of China 91859119National Public Welfare Basic Scientific Research Project of Chinese Academy of Medical Sciences 2018PT32003National Public Welfare Basic Scientific Research Project of Chinese Academy of Medical Sciences 2019PT320008
6 · The paper itself

Abstract

backgroundRenal calculi are a common and recurrent urological disease and are usually detected by CT. In this study, we evaluated the diagnostic capability, image quality, and radiation dose of abdominal ultra-low-dose CT (ULDCT) with deep learning reconstruction (DLR) for detecting renal calculi.

methodsSixty patients with suspected renal calculi were prospectively enrolled. Low-dose CT (LDCT) images were reconstructed with hybrid iterative reconstruction (LD-HIR) and was regarded as the standard for stone and lesion detection. ULDCT images were reconstructed with HIR (ULD-HIR) and DLR (ULD-DLR). We then compared stone detection rate, abdominal lesion detection rate, image quality and radiation dose between LDCT and ULDCT.

resultsA total of 130 calculi were observed on LD-HIR images. Stone detection rates of ULD-HIR and ULD-DLR images were 93.1% (121/130) and 95.4% (124/130). A total of 129 lesions were detected on the LD-HIR images. The lesion detection rate on ULD-DLR images was 92.2%, with 10 cysts < 5 mm in diameter missed. The CT values of organs on ULD-DLR were similar to those on LD-HIR and lower than those on ULD-HIR. Signal-to-noise ratio was highest and noise lowest on ULD-DLR. The subjective image quality of ULD-DLR was similar to that of LD-HIR and better than that of ULD-HIR. The effective radiation dose of ULDCT (0.64 ± 0.17 mSv) was 77% lower than that of LDCT (2.75 ± 0.50 mSv).

conclusionULDCT combined with DLR could significantly reduce radiation dose while maintaining suitable image quality and stone detection rate in the diagnosis of renal calculi.

Indexed as

Abdominal CTDeep learning reconstructionRenal calculiUltra-low-dose CT

Identifiers

PMID36209195
PMCPMC9547757
OpenAlexW4303672089

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.