Evidence map›Paper›PMID 36209054›Full record

ArticleBMC neurology2022

Effects of endovascular treatment and prognostic factors for recovery of oculomotor nerve palsy caused by posterior communicating artery aneurysms: a multi-center retrospective analysis.

Bin Wang, Sheng Liu, Shi-Jie Na, Ya Peng, Wen-Bin Ding, Lin-Bo Zhao, Zhen-Yu Jia, Hai-Bin Shi, Qing Feng

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in BMC neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Bin WangDepartment of Interventional Radiology, The First Affiliated Hospital of Nanjing Medical University, 210029, Nanjing, China.
Sheng LiuDepartment of Interventional Radiology, The First Affiliated Hospital of Nanjing Medical University, 210029, Nanjing, China.
Shi-Jie NaDepartment of Neurosurgery, Nanjing Drum Tower Hospital, Nanjing University Medical School, 210008, Nanjing, China.
Ya PengDepartment of Neurosurgery, The Third Affiliated Hospital of Soochow University, 213003, Changzhou, China.
Wen-Bin DingDepartment of Intervention Radiology, the Second Affiliated Hospital of Nantong University, 226001, Nantong, China.
Lin-Bo ZhaoDepartment of Interventional Radiology, The First Affiliated Hospital of Nanjing Medical University, 210029, Nanjing, China.
Zhen-Yu JiaDepartment of Interventional Radiology, The First Affiliated Hospital of Nanjing Medical University, 210029, Nanjing, China.
Hai-Bin ShiDepartment of Interventional Radiology, The First Affiliated Hospital of Nanjing Medical University, 210029, Nanjing, China.
Qing FengDepartment of Nutrition and Food Hygiene, School of Public Health, Nanjing Medical University, 101 Longmian Avenue, 211166, Nanjing, China. qingfeng@njmu.edu.cn.
Jiangsu Province Hospital · CNNanjing Drum Tower Hospital · CNNanjing Medical University · CNNantong University · CNSoochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOculomotor nerve palsy (ONP) may result from posterior communicating artery (PcomA) aneurysms. We aimed to evaluate the resolution of ONP after endovascular treatment with the intention of clarifying predictors of nerve recovery in a relatively large series.

methodsA total of 211 patients with ONP caused by PcomA aneurysms underwent endovascular coiling between May 2010 and December 2020 in four tertiary hospitals. We evaluated the demographics, clinical characteristics, aneurysm morphology parameters and ONP resolution to analyze the predictors of ONP recovery using univariate and multivariate analyses.

resultsAt the last available clinical follow-up, ONP resolution was complete in 126 (59.7%) patients, partial in 73 (34.6%) patients, and no recovery in 12 (5.7%) patients. The median resolution time after endovascular treatment was 55 days (interquartile range: 40-90 days). In multivariate analysis, degree of ONP (incomplete palsy) on admission (OR 5.396; 95% CI 2.836-10.266; P < 0.001), duration of ONP (≤ 14 days) before treatment (OR 5.940; 95% CI 2.724-12.954; P < 0.001) were statistically significant predictors of complete recovery of ONP. In the subgroup analysis of patients with unruptured aneurysms, aspirin showed a higher complete recovery rate in univariate analysis (OR 2.652; 95% CI 1.057-6.656; P = 0.038).

conclusionInitial incomplete ONP and early management might predict better recovery of ONP after endovascular treatment.

Indexed as

Embolization, TherapeuticEndovascular ProceduresIntracranial AneurysmOculomotor Nerve DiseasesAspirinHumansPrognosisRetrospective StudiesTreatment OutcomeAspirinEndovascular treatmentOculomotor nerve palsyPosterior communicating artery aneurysmPrognostic factor

Identifiers

PMID36209054
PMCPMC9547414
OpenAlexW4303628921

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.