Trial reportBMC pediatrics2022
Early child stimulation, linear growth and neurodevelopment in low birth weight infants.
Trial report in BMC pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02631343 (A Community-based Model of Delivery of Kangaroo Mother Care for Improving Child Survival and Brain Development in Low Birth Weight Newborns), which is not on this map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Community-based Model of Delivery of Kangaroo Mother Care for Improving Child Survival and Brain Development in Low Birth Weight Newborns
Who cites it
11 citing papers in PubMed, 14 citations in OpenAlex.
- Identification of characteristic genes of pressure ulcers based on angiogenesis-related genes and construction of miRNA, transcription factor, and molecular drug regulatory networks.BMC immunology · 2026Article
- Socioeconomic disparities and health-related parenting practices in shaping early infant neurodevelopment: evidence from a Chinese prospective birth cohort.BMC pregnancy and childbirth · 2026Article
- Longitudinal Trajectories of Growth and Development in HIV-Exposed Uninfected Children from a Long-Term Birth Cohort - 8 Regions, 3 PLADs, China, 2017-2024.China CDC weekly · 2026Article
- Increasing length board use in a neonatal intensive care unit: a quality improvement initiative.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Impact of Different Maternal Age Subgroups on Pregnancy Adverse Outcomes in China: A Multicenter Cohort Study.Health science reports · 2026Article
- The potential pathway from maternal intimate partner violence to early childhood development through height-for-age z-score: evidence from 10 low- and middle-income countries.Frontiers in public health · 2026Article
- Neurodevelopment and Risk Factors in Infants Before, During, and After the COVID-19 Pandemic in Eastern China: Cross-Sectional Study.JMIR public health and surveillance · 2025Article
- Prevalence and determinants of undernutrition in the urban slums of Belagavi: a cross-sectional study among young children.Frontiers in pediatrics · 2025Article
- Barriers and facilitators to the implementation of the kangaroo mother care in NICUs of high-income and low- and middle-income countries: a scoping review.Frontiers in public health · 2025Review
- Short-term neonatal and long-term neurodevelopmental outcome of children born term low birth weight.Scientific reports · 2024Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 6 institutions in 4 countries.
Funding
Abstract
backgroundChildren with low birth weight (LBW) are at risk of linear growth faltering and developmental deficits. Evidence suggests that early child stimulation and care reflected as responsive caregiving and opportunities for learning can promote development. The current analysis aimed to measure the extent to which linear growth and early child stimulation modify each other's association with neurodevelopmental outcomes among LBW infants.
methodsThis is a secondary data analyses from a randomized controlled trial on the effect of community-initiated kangaroo mother care in LBW infants on their neurodevelopment at 12 months of corrected age. Bayley Scales of Infant and Toddler Development was used to assess cognitive, motor and language scores. Stimulation at home was assessed by the Pediatric Review of Children's Environmental Support and Stimulation (PROCESS) tool. PROCESS scores were categorized into three groups: < Mean-1SD (low stimulation); Mean ± 1 SD (moderate stimulation) and > mean + 1SD (high stimulation).
resultsA total of 516 infants were available for neurodevelopment assessments. Interactions were observed between length for age z-score (LAZ) and PROCESS score categories. In the low stimulation group, the adjusted regression coefficients for the association between LAZ and cognitive, motor and language scores were substantially higher than in the moderate and high stimulation group. Stimulation was positively associated with neurodevelopmental outcomes in both stunted and non-stunted infants; however, the association was twice as strong in stunted than in non-stunted.
conclusionModerate to high quality stimulation may alleviate the risk of sub-optimal development in LBW infants with linear growth deficits. CLINICAL
trial registrationThe primary trial whose data are analysed is registered at clinicaltrials.gov ( https://clinicaltrials.gov/ct2/show/NCT02631343 ).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.