Evidence map›Paper›PMID 36208859›Full record

ArticleMolecular and cellular neurosciences2022

Cypin binds to tubulin heterodimers and microtubule protofilaments and regulates microtubule spacing in developing hippocampal neurons.

Eric S Sweet, Keith R Lange, Madeleine R Fenner, Chia-Yi Tseng, Barbara F Akum, Bonnie L Firestein

Open access · greenAbstract read
In one paragraph

Article in Molecular and cellular neurosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Eric S SweetDepartment of Biology, West Chester University, West Chester, PA, United States of America.
Keith R LangeDepartment of Cell Biology and Neuroscience, Rutgers, The State University of New Jersey, Piscataway, NJ, United States of America; Molecular Biosciences Graduate Program, Rutgers, The State University of New Jersey, Piscataway, NJ, United States of America.
Madeleine R FennerDepartment of Cell Biology and Neuroscience, Rutgers, The State University of New Jersey, Piscataway, NJ, United States of America.
Chia-Yi TsengDepartment of Cell Biology and Neuroscience, Rutgers, The State University of New Jersey, Piscataway, NJ, United States of America; Neurosciences Graduate Program, Rutgers, The State University of New Jersey, Piscataway, NJ, United States of America.
Barbara F AkumDepartment of Cell Biology and Neuroscience, Rutgers, The State University of New Jersey, Piscataway, NJ, United States of America; Molecular Biosciences Graduate Program, Rutgers, The State University of New Jersey, Piscataway, NJ, United States of America.
Bonnie L FiresteinDepartment of Cell Biology and Neuroscience, Rutgers, The State University of New Jersey, Piscataway, NJ, United States of America. Electronic address: firestein@biology.rutgers.edu.
Rutgers, The State University of New Jersey · USWest Chester University · US

Funding

UMDNJ TRAINING GRANT IN BIOTECHNOLOGYT32GM008339 · NIGMS · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI YARMUSH, MARTIN L · 1989 to 2019
$6.1M
Training in Translating Neuroscience to TherapiesT32NS115700 · NINDS · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI MOURADIAN, M. MARAL · 2021 to 2025
$1.4M
MOLECULAR AND DEVELOPMENT BASIS OF MENTAL ILLNESST32MH019957 · NIMH · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI PINTAR, JOHN E · 1996 to 2007
$1.1M
NIGMS NIH HHS T32 GM008339NIMH NIH HHS T32 MH019957NINDS NIH HHS T32 NS115700
6 · The paper itself

Abstract

Cytosolic PSD-95 interactor (cypin) is a multifunctional, guanine deaminase that plays a major role in shaping the morphology of the dendritic arbor of hippocampal and cortical neurons. Cypin catalyzes the Zn

Indexed as

DendritesTubulinAmino AcidsCarrier ProteinsDisks Large Homolog 4 ProteinHippocampusMicrotubulesMolecular Docking SimulationNeuronsAmino AcidsCarrier ProteinsDisks Large Homolog 4 ProteinTubulinCytosolic PSD-95 interactorHippocampal neuronMicrotubule polymerizationMicrotubule protofilamentTubulin heterodimer

Identifiers

PMID36208859
PMCPMC11835482
OpenAlexW4302011001

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.