Evidence map›Paper›PMID 36208809›Full record

ArticleInternational journal of biological macromolecules2022

The inhibitory activity of methoxyl flavonoids derived from Inula britannica flowers on SARS-CoV-2 3CLpro.

Jang Hoon Kim, Yea-In Park, Mok Hur, Woo Tae Park, Youn-Ho Moon, Sung Cheol Koo, Her Yun-Chan, Ik Soo Lee, Junsoo Park

Abstract read
In one paragraph

Article in International journal of biological macromolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Inhibition by components ofJournal of enzyme inhibition and medicinal chemistry · 2023
    Article
  5. Eupatin, a Flavonoid, Inhibits Coronavirus 3CL Protease and Replication.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jang Hoon KimDepartment of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Eumsung 27709, Republic of Korea.
Yea-In ParkDivision of Biological Science and Technology, Yonsei University, Wonju 26493, Republic of Korea.
Mok HurDepartment of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Eumsung 27709, Republic of Korea.
Woo Tae ParkDepartment of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Eumsung 27709, Republic of Korea.
Youn-Ho MoonDepartment of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Eumsung 27709, Republic of Korea.
Sung Cheol KooDepartment of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Eumsung 27709, Republic of Korea.
Her Yun-ChanDepartment of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Eumsung 27709, Republic of Korea.
Ik Soo LeeKm Covergence Research Division, Korea Institute of Oriental Medicien, Daejeon, Republic of Korea. Electronic address: knifer48@kiom.re.kr.
Junsoo ParkDivision of Biological Science and Technology, Yonsei University, Wonju 26493, Republic of Korea. Electronic address: junsoo@yonsei.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In our ongoing efforts to identify effective natural antiviral agents, four methoxy flavonoids (1-4) were isolated from the Inula britannica flower extract. Their structures were elucidated using nuclear magnetic resonance. Flavonoids 1-4 exhibited inhibitory activity against SARS- CoV-2 3CLpro with IC

Indexed as

COVID-19InulaAntiviral AgentsFlavonoidsFlowersSARS-CoV-2Antiviral AgentsFlavonoids3CLproHCoV-OC43Inula britannicaMethoxyl flavonoidsSARS-CoV-2

Identifiers

PMID36208809
PMCPMC9534544

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.