Evidence map›Paper›PMID 36208718›Full record

ArticleContemporary clinical trials2022

Cognitive rehabilitation in post-COVID-19 condition: A study protocol for a randomized controlled trial.

Bjørn Ingulfsvann Hagen, Anners Lerdal, Arne Søraas, Nils Inge Landrø, Ragnhild Bø, Milada Cvancarova Småstuen, Jacqueline Becker, Jan Stubberud

Registry-linked trialOpen access · hybridAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Contemporary clinical trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05494424 (Cognitive Rehabilitation in Post-COVID-19 Condition), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05494424 naactive not recruitingnot on this mapstarted 2023, after this paper: background citation

Cognitive Rehabilitation in Post-COVID-19 Condition: A Study Protocol for a Randomized Controlled Trial

TypeinterventionalSponsorLovisenberg Diakonale HospitalRan2023 to 2028Enrolled135ConditionsCOVID-19ArmsGoal Management Training (GMT)
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Bjørn Ingulfsvann HagenDepartment of Social Education, UiT - The Arctic University of Norway, Harstad, Norway; Department of Research, Lovisenberg Diaconal Hospital, Oslo, Norway. Electronic address: bha060@uit.no.
Anners LerdalDepartment of Research, Lovisenberg Diaconal Hospital, Oslo, Norway.
Arne SøraasDepartment of Microbiology, Oslo University Hospital, Oslo, Norway.
Nils Inge LandrøDepartment of Psychology, University of Oslo, Oslo, Norway.
Ragnhild BøDepartment of Psychology, University of Oslo, Oslo, Norway.
Milada Cvancarova SmåstuenDepartment of Research, Lovisenberg Diaconal Hospital, Oslo, Norway.
Jacqueline BeckerDepartment of Medicine, Icahn School of Medicine at Mount Sinai, New York City, USA.
Jan StubberudDepartment of Research, Lovisenberg Diaconal Hospital, Oslo, Norway; Department of Psychology, University of Oslo, Oslo, Norway.
Lovisenberg Diakonale Høgskole · NOUniversity of Oslo · NOIcahn School of Medicine at Mount Sinai · USOslo University Hospital · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPost-COVID-19 condition is frequently comprised of persistent cognitive sequela, including deficits in attention and executive functions (EFs), which can act as a barrier for regaining pre-illness functional levels. Goal Management Training (GMT) is a cognitive rehabilitation (CR) intervention for improving attention and EFs that has received empirical support in studies of other patient groups. The present study aims to determine the efficacy of GMT for improving everyday attention and EFs in adults who experience persistent cognitive deficits after COVID-19.

methodsThis study protocol describes an open-label randomized controlled trial comparing the efficacy of GMT to a wait list control condition (WL), for improving persistent (> 2 months) cognitive sequela in post-COVID-19 condition. The study aims to recruit 240 participants aged 18 to 65 years with a history of SARS-CoV-2 infection and perceived attentional and EF difficulties in daily life. Participants will be block randomized (computer-algorithm) to either group-based GMT (n = 120) or WL (n = 120). GMT will be internet-delivered to groups of six participants in six two-hour sessions delivered once a week. The primary outcome will be the Metacognition Index of the Behavior Rating Inventory of Executive Function - Adult Version, a self-report measure assessing everyday EF difficulties, specifically metacognition, at six months post-treatment. Secondary outcomes include performance-based neurocognitive measures, and tertiary outcomes include rating scales of cognition, emotional health, quality of life, and fatigue.

conclusionStudy findings could contribute to providing an evidence-based treatment option for symptoms that are frequent and debilitating following a prevalent condition. TRIAL REGISTRATION NUMBER: NCT05494424.

Indexed as

Cognitive Behavioral TherapyCOVID-19AdultCognitionHumansQuality of LifeRandomized Controlled Trials as TopicSARS-CoV-2Surveys and QuestionnairesTreatment OutcomeCognitionCognitive rehabilitationCOVID-19Executive functionsRandomized controlled trial

Identifiers

PMID36208718
PMCPMC9533592
OpenAlexW4302009062

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.