Evidence map›Paper›PMID 36208022›Full record

ArticleMolecular ecology2022

Inbreeding effects on telomeres in hatchling sand lizards (Lacerta agilis): An optimal family affair?

Mats Olsson, Badreddine Bererhi, Emily Miller, Tonia Schwartz, Nicky Rollings, Willow Lindsay, Erik Wapstra

Open access · greenAbstract read
In one paragraph

Article in Molecular ecology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Mats OlssonDepartment of Biological and Environmental Sciences, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0002-4130-1323
Badreddine BererhiDepartment of Biological and Environmental Sciences, University of Gothenburg, Gothenburg, Sweden.
Emily MillerSydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.
Tonia SchwartzBiological Sciences, Auburn University, Auburn, Alabama, USA.ORCID 0000-0002-7712-2810
Nicky RollingsSchool of Life and Environmental Sciences, The University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0002-9411-5129
Willow LindsayDepartment of Biological and Environmental Sciences, University of Gothenburg, Gothenburg, Sweden.
Erik WapstraSchool of Natural Sciences, University of Tasmania, Hobart, Tasmania, Australia.
The University of Sydney · AUUniversity of Gothenburg · SEAuburn University · USUniversity of Tasmania · AUUniversity of Wollongong · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Telomeres are nucleotide-protein caps, predominantly at the ends of Metazoan linear chromosomes, showing complex dynamics with regard to their lengthening and shortening through life. Their complexity has entertained the idea that net telomere length and attrition could be valuable biomarkers of phenotypic and genetic quality of their bearer. Intuitively, those individuals could be more heterozygous and, hence, less inbred. However, some inbred taxa have longer, not shorter, telomeres. To understand the role of inbreeding in this complex scenario we need large samples across a range of genotypes with known maternity and paternity in telomere-screened organisms under natural conditions. We assessed the effects of parental and hatchling inbreeding on telomere length in >1300 offspring from >500 sires and dams in a population of sand lizards (Lacerta agilis). Maternal and paternal ID and their interactions predict hatchling telomere length at substantial effect sizes (R

Indexed as

InbreedingLizardsAnimalsFemaleGenotypeHumansPregnancyTelomereTelomere Shorteninghatchling telomere length (T/S ratio)Lacerta agilisparental effectssand lizardstandardized heterozygosity (SH)

Identifiers

PMID36208022
PMCPMC10092626
OpenAlexW4303633949

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.