ArticleNature communications2022
Past and present giant viruses diversity explored through permafrost metagenomics.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed.
- Article
- Giant viruses of the polar regions: diversity, endemism, adaptation and ecological structuring.FEMS microbiology ecology · 2026Review
- Rise of the viral giants: common themes underlying genome gigantism in eukaryotic viruses and bacteriophages.Current opinion in microbiology · 2026Review
- Review
- Article
- DNA virus-host patterns in lake and marine environments over the last glacial cycle.The ISME journal · 2026Article
- Widespread and intron-rich mirusviruses are predicted to reproduce in nuclei of unicellular eukaryotes.Nature microbiology · 2026Article
- Phage-plasmid-like elements are found throughout diverse environments and encode niche-specific functional traits.PloS one · 2026Article
- Integrative genomic analyses support the division of the extendedJournal of virology · 2025Review
- Giant DNA viruses encode a hallmark translation initiation complex of eukaryotic life.bioRxiv : the preprint server for biology · 2025Article
- Naiavirus: an enveloped giant virus with a pleomorphic, flexible tail.Nature communications · 2025Article
- Evolutionarily conserved grammar rules viral factories of amoeba-infecting members of the hyperdiverseProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Refining the taxonomy of pithovirus-related giant DNA viruses within the order Pimascovirales.Archives of virology · 2025Article
- Article
- Review
- 20 years of research on giant viruses.Npj viruses · 2025Review
- Cytochrome b5 occurrence in giant and other viruses belonging to the phylum Nucleocytoviricota.Npj viruses · 2025Article
- Vertical transport and spatiotemporal dynamics of giant viruses in the North Pacific subtropical gyre.The ISME journal · 2025Article
- Pacmanvirus isolated from the Lost City hydrothermal field extends the concept of transpoviron beyond the family Mimiviridae.The ISME journal · 2025Article
- Complex transcriptional regulations of a hyperparasitic quadripartite system in giant viruses infecting protists.Nature communications · 2024Article
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5 authors.
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Abstract
Giant viruses are abundant in aquatic environments and ecologically important through the metabolic reprogramming of their hosts. Less is known about giant viruses from soil even though two of them, belonging to two different viral families, were reactivated from 30,000-y-old permafrost samples. This suggests an untapped diversity of Nucleocytoviricota in this environment. Through permafrost metagenomics we reveal a unique diversity pattern and a high heterogeneity in the abundance of giant viruses, representing up to 12% of the sum of sequence coverage in one sample. Pithoviridae and Orpheoviridae-like viruses were the most important contributors. A complete 1.6 Mb Pithoviridae-like circular genome was also assembled from a 42,000-y-old sample. The annotation of the permafrost viral sequences revealed a patchwork of predicted functions amidst a larger reservoir of genes of unknown functions. Finally, the phylogenetic reconstructions not only revealed gene transfers between cells and viruses, but also between viruses from different families.
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