ArticleNature communications2022
GWAS, MWAS and mGWAS provide insights into precision agriculture based on genotype-dependent microbial effects in foxtail millet.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.
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Who cites it
78 citing papers in PubMed, 135 citations in OpenAlex.
- Host genetic variation is associated with root-associated microbiome assembly and resistance to Fusarium oxysporum in tobacco.Plant physiology · 2026Article
- ZmHPATR1 orchestrates phyllosphere organic acid flux to recruit Sphingomonas and enhance resistance of maize to Curvularia leaf spot.The New phytologist · 2026Article
- Wild rice locus enables microbiome re-domestication for enhanced nitrogen-use efficiency.Nature microbiology · 2026Article
- Genetic dissection of the eggplant rhizosphere microbiome enables microbiome-assisted breeding.Horticulture research · 2026Article
- Microbial terroir in winegrowing: revisiting the role of microbial biogeography in terroir expression.Applied and environmental microbiology · 2026Review
- The functional structure of foxtail millet rhizoplane microbiome and its association with yield.Microbiology spectrum · 2026Article
- Review
- Deciphering the genetic basis of nodule number through integrative analysis of host genotype and endophytes.Journal of advanced research · 2026Article
- Distinct rhizosphere microbiomes and metabolomes mediate Fusarium crown rot resistance across wheat cultivars.NPJ biofilms and microbiomes · 2026Article
- On the genetic origins of phenotypes in genome-wide association studies: the SAFE-hBMC bioinformatics · 2026Article
- Plant health in the era of global changes, holobiont biology, and microbiome-based solutions.Horticulture research · 2026Article
- Review
- Identifying genetic loci associated with drought tolerance in foxtail millet (Setaria italica).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Article
- Amino-acid-transporter-mediated assembly of rhizosphere microbiota enhances soil organic nitrogen acquisition in rice.Nature plants · 2026Article
- Large-scale multi-omics unveils host-microbiome interactions driving root development and nitrogen acquisition.Nature plants · 2026Article
- Printing technologies for monitoring crop health.Nature communications · 2026Review
- Breeding effects on the root-associated microbiome ofISME communications · 2026Article
- Symbiotic interactions of plant microbiota in alleviating stress: a review.Frontiers in plant science · 2026Review
- Deciphering the role of NtabCrRLK47 in rhizosphere microbiome remodeling and tobacco growth promotion.Frontiers in plant science · 2026Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Genetic and environmental factors collectively determine plant growth and yield. In the past 20 years, genome-wide association studies (GWAS) have been conducted on crops to decipher genetic loci that contribute to growth and yield, however, plant genotype appears to be insufficient to explain the trait variations. Here, we unravel the associations between genotypic, phenotypic, and rhizoplane microbiota variables of 827 foxtail millet cultivars by an integrated GWAS, microbiome-wide association studies (MWAS) and microbiome genome-wide association studies (mGWAS) method. We identify 257 rhizoplane microbial biomarkers associated with six key agronomic traits and validated the microbial-mediated growth effects on foxtail millet using marker strains isolated from the field. The rhizoplane microbiota composition is mainly driven by variations in plant genes related to immunity, metabolites, hormone signaling and nutrient uptake. Among these, the host immune gene FLS2 and transcription factor bHLH35 are widely associated with the microbial taxa of the rhizoplane. We further uncover a plant genotype-microbiota interaction network that contributes to phenotype plasticity. The microbial-mediated growth effects on foxtail millet are dependent on the host genotype, suggesting that precision microbiome management could be used to engineer high-yielding cultivars in agriculture systems.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.