Evidence map›Paper›PMID 36207131›Full record

ArticleEuropean journal of hospital pharmacy : science and practice2023

COVID-19 vaccine triggered autoimmune hepatitis: case report.

Merrin Mathew, Sheba Baby John, Juny Sebastian, Mandyam Dhati Ravi

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in European journal of hospital pharmacy : science and practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Correspondence on 'COVID-19 vaccine triggered autoimmune hepatitis: case report' by MathewEuropean journal of hospital pharmacy : science and practice · 2023
    Article
  6. COVID-19 vaccine triggered autoimmune hepatitis: case report.European journal of hospital pharmacy : science and practice · 2023
    Article
  7. Article
  8. Autoimmune liver diseases and SARS-CoV-2.World journal of gastroenterology · 2023
    Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Merrin MathewDepartment of Pharmacy Practice, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Mysuru, Karnataka, India.ORCID 0000-0002-6354-2312
Sheba Baby JohnDepartment of Pharmacy Practice, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Mysuru, Karnataka, India.
Juny SebastianDepartment of Pharmacy Practice, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Mysuru, Karnataka, India dr.junysebastian@gmu.ac.ae.ORCID 0000-0002-4626-8729
Mandyam Dhati RaviDepartment of Pharmacy Practice, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Mysuru, Karnataka, India.
JSS Academy of Higher Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoimmune hepatitis (AIH) is a non-contagious, chronic, inflammatory autoimmune disease in which one's own immune system attacks healthy, normal hepatic cells. The exact cause of AIH is unknown; however, the combination of genetic, environmental (eg, drugs and natural infection) and immunological factors may lead to AIH. AIH may also be potentiated with the use of vaccines: this case reports one such event following immunisation, along with 1 year of follow-up. A female patient in her late 20s presented to the hospital with yellowish discolouration of eyes, urine and stools. Her medical history revealed that she had been vaccinated with the first dose of a COVID-19 vaccine 10 days earlier. She had a history of asymptomatic COVID-19 infection 3 months ago and a history of chronic analgesic consumption for migraine. She was diagnosed as having AIH through extensive clinical and laboratory workup. This case may be an immediate enhancement of a hidden autoimmune disorder triggered by the vaccination. This adverse event following immunisation has an adequate temporal relationship with her COVID-19 vaccine. The causality can be categorised as 'indeterminate' and may be considered as a potential signal following COVID-19 vaccination.

Indexed as

COVID-19 VaccinesHepatitis, AutoimmuneAdultCOVID-19FemaleHumansVaccinationCOVID-19 VaccinesALLERGY AND IMMUNOLOGYCOVID-19DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONSImmunizationPHARMACY SERVICE, HOSPITALSafety

Identifiers

PMID36207131
PMCPMC10447947
OpenAlexW4303453800

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.