Evidence map›Paper›PMID 36207130›Full record

ArticleCold Spring Harbor molecular case studies2022

Lorlatinib and compound mutations in ALK+ large-cell neuroendocrine lung carcinoma: a case report.

Christiane Wiedemann, Daniel Kazdal, Jelena Cvetkovic, Julia Kunz, David Fisch, Martina Kirchner, Mark Kriegsmann, Holger Sültmann, Claus-Peter Heussel, Helge Bischoff and 3 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cold Spring Harbor molecular case studies, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. An advanced NSCLC patient withTranslational lung cancer research · 2023
    Article
  7. Article
  8. Transformation ofTranslational lung cancer research · 2023
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Christiane Wiedemann *Department of Thoracic Oncology, Thoraxklinik at Heidelberg University Hospital and National Center for Tumor Diseases, Heidelberg, 69126 Germany.
Daniel Kazdal *Institute of Pathology, Heidelberg University Hospital, Heidelberg, 69120 Germany.
Jelena CvetkovicDepartment of Thoracic Oncology, Thoraxklinik at Heidelberg University Hospital and National Center for Tumor Diseases, Heidelberg, 69126 Germany.
Julia KunzDepartment of Thoracic Oncology, Thoraxklinik at Heidelberg University Hospital and National Center for Tumor Diseases, Heidelberg, 69126 Germany.
David FischDepartment of Thoracic Oncology, Thoraxklinik at Heidelberg University Hospital and National Center for Tumor Diseases, Heidelberg, 69126 Germany.
Martina KirchnerInstitute of Pathology, Heidelberg University Hospital, Heidelberg, 69120 Germany.
Mark KriegsmannInstitute of Pathology, Heidelberg University Hospital, Heidelberg, 69120 Germany.
Holger SültmannTranslational Lung Research Center Heidelberg (TLRC-H), member of the German Center for Lung Research (DZL), Heidelberg, 69120 Germany.
Claus-Peter HeusselTranslational Lung Research Center Heidelberg (TLRC-H), member of the German Center for Lung Research (DZL), Heidelberg, 69120 Germany.
Helge BischoffDepartment of Thoracic Oncology, Thoraxklinik at Heidelberg University Hospital and National Center for Tumor Diseases, Heidelberg, 69126 Germany.
Michael ThomasDepartment of Thoracic Oncology, Thoraxklinik at Heidelberg University Hospital and National Center for Tumor Diseases, Heidelberg, 69126 Germany.
Albrecht StenzingerInstitute of Pathology, Heidelberg University Hospital, Heidelberg, 69120 Germany.
Petros ChristopoulosDepartment of Thoracic Oncology, Thoraxklinik at Heidelberg University Hospital and National Center for Tumor Diseases, Heidelberg, 69126 Germany.
German Center for Lung Research · DEHeidelberg University · DEUniversity Hospital Heidelberg · DENational Center for Tumor Diseases · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Large-cell neuroendocrine lung carcinoma (LCNEC) is a high-grade neoplasm with median survival of 1 year and limited therapeutic options. Here, we report the unusual case of a 47-yr-old female smoker with stage IV LCNEC featuring

Indexed as

Breast NeoplasmsCarcinomaCarcinoma, Non-Small-Cell LungLung NeoplasmsAminopyridinesAnaplastic Lymphoma KinaseCrizotinibDrug Resistance, NeoplasmFemaleHumansLactamsLactams, MacrocyclicLungMastectomyMutationOrganophosphorus CompoundsAminopyridinesAnaplastic Lymphoma KinasebrigatinibceritinibCrizotinibLactamsLactams, MacrocycliclorlatinibOrganophosphorus CompoundsPyrazolesPyrimidinesReceptor Protein-Tyrosine KinasesSulfoneslung adenocarcinoma

Identifiers

PMID36207130
PMCPMC9632356
OpenAlexW4303457059

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.