ArticleNeuroImage2022
Spontaneous sensorimotor beta power and cortical thickness uniquely predict motor function in healthy aging.
Article in NeuroImage, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Dissociable effects of β-tACS on spectral power and network organization for proximal versus distal upper-limb recovery in subacute stroke: double-blind, randomized, sham-controlled trial with high-density EEG.Journal of neuroengineering and rehabilitation · 2026Trial
- Age-Related Changes in Spontaneous Brain Dynamics Revealed by Resting-State Magnetoencephalography.GeroScience · 2026Article
- Article
- Structure-function coupling of large-scale cortical networks across the lifespan is spectrally specific.Communications biology · 2026Article
- Normative modeling of MEG brain oscillations across the human lifespan.Communications biology · 2026Article
- Divergence of cortical neurophysiology across different neurodegenerative disorders compared to healthy ageing.Progress in neurobiology · 2026Article
- Adults with Down syndrome display altered entrainment of occipital cortical neurons.Brain communications · 2026Article
- Mobility Function and Aperiodic Electrocortical Activity in Younger and Older Adults.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2026Article
- Changes of EEG beta band power and functional connectivity during spaceflight: a retrospective study.Scientific reports · 2025Article
- Age-related changes in neural oscillations vary as a function of brain region and frequency band.Frontiers in aging neuroscience · 2025Article
- Aging modulates the impact of cognitive interference subtypes on dynamic connectivity across a distributed motor network.npj aging · 2024Article
- Regular cannabis use modulates gamma activity in brain regions serving motor control.Journal of psychopharmacology (Oxford, England) · 2024Article
- Healthy aging alters the oscillatory dynamics and fronto-parietal connectivity serving fluid intelligence.Human brain mapping · 2024Article
- The cortical neurophysiological signature of amyotrophic lateral sclerosis.Brain communications · 2024Article
- Spontaneous cortical activity is altered in persons with HIV and related to domain-specific cognitive function.Brain communications · 2024Article
- Developmental differences in functional organization of multispectral networks.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Spontaneous cortical dynamics from the first years to the golden years.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Overcoming harmonic hurdles: Genuine beta-band rhythms vs. contributions of alpha-band waveform shape.Imaging neuroscience (Cambridge, Mass.) · 2023Article
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6 authors.
Funding
Abstract
backgroundSpontaneous beta activity in the primary motor cortices has been shown to increase in amplitude with advancing age, and that such increases are tightly coupled to stronger motor-related beta oscillations during movement planning. However, the relationship between these age-related changes in spontaneous beta in the motor cortices, local cortical thickness, and overall motor function remains unclear.
methodsWe collected resting-state magnetoencephalography (MEG), high-resolution structural MRI, and motor function scores using a neuropsychological battery from 126 healthy adults (56 female; age range = 22-72 years). MEG data were source-imaged and a whole-brain vertex-wise regression model was used to assess age-related differences in spontaneous beta power across the cortex. Cortical thickness was computed from the structural MRI data and local beta power and cortical thickness values were extracted from the sensorimotor cortices. To determine the unique contribution of age, spontaneous beta power, and cortical thickness to the prediction of motor function, a hierarchical regression approach was used.
resultsThere was an increase in spontaneous beta power with age across the cortex, with the strongest increase being centered on the sensorimotor cortices. Sensorimotor cortical thickness was not related to spontaneous beta power, above and beyond age. Interestingly, both cortical thickness and spontaneous beta power in sensorimotor regions each uniquely contributed to the prediction of motor function when controlling for age. DISCUSSION: This multimodal study showed that cortical thickness and spontaneous beta activity in the sensorimotor cortices have dissociable contributions to motor function across the adult lifespan. These findings highlight the complexity of interactions between structure and function and the importance of understanding these interactions in order to advance our understanding of healthy aging and disease.
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