Evidence map›Paper›PMID 36206606›Full record

ArticleVirology2022

SARS-CoV-2 and influenza co-infection: A cross-sectional study in central Missouri during the 2021-2022 influenza season.

Cynthia Y Tang, Maria Boftsi, Lindsay Staudt, Jane A McElroy, Tao Li, Sabrina Duong, Adrienne Ohler, Detlef Ritter, Richard Hammer, Jun Hang and 1 more

Open access · greenAbstract read
In one paragraph

Article in Virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

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  17. Anti-Influenza Virus Activity ofFoods (Basel, Switzerland) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Cynthia Y TangCenter for Influenza and Emerging Infectious Diseases, University of Missouri, Columbia, MO, USA; Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia, MO, USA; Bond Life Sciences Center, University of Missouri, Columbia, MO, USA; Institute for Data Science and Informatics, University of Missouri, Columbia, MO, USA.
Maria BoftsiCenter for Influenza and Emerging Infectious Diseases, University of Missouri, Columbia, MO, USA; Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia, MO, USA; Bond Life Sciences Center, University of Missouri, Columbia, MO, USA.
Lindsay StaudtCenter for Influenza and Emerging Infectious Diseases, University of Missouri, Columbia, MO, USA; Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia, MO, USA; Bond Life Sciences Center, University of Missouri, Columbia, MO, USA.
Jane A McElroyFamily and Community Medicine, University of Missouri, Columbia, MO, USA.
Tao LiViral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Sabrina DuongCenter for Influenza and Emerging Infectious Diseases, University of Missouri, Columbia, MO, USA; Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia, MO, USA; Bond Life Sciences Center, University of Missouri, Columbia, MO, USA.
Adrienne OhlerChild Health, School of Medicine, University of Missouri, Columbia, MO, USA.
Detlef RitterPathology and Anatomical Sciences, School of Medicine, University of Missouri, Columbia, MO, USA.
Richard HammerInstitute for Data Science and Informatics, University of Missouri, Columbia, MO, USA; Pathology and Anatomical Sciences, School of Medicine, University of Missouri, Columbia, MO, USA.
Jun HangViral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Xiu-Feng WanCenter for Influenza and Emerging Infectious Diseases, University of Missouri, Columbia, MO, USA; Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia, MO, USA; Bond Life Sciences Center, University of Missouri, Columbia, MO, USA; Institute for Data Science and Informatics, University of Missouri, Columbia, MO, USA; Department of Electrical Engineering & Computer Science, College of Engineering, University of Missouri, Columbia, MO, USA. Electronic address: wanx@missouri.edu.
University of Missouri · USWalter Reed Army Institute of Research · USUniversity of Missouri Health System · US

Funding

Impact of repeated vaccination on the effectiveness of seasonal influenza vaccinesR01AI152521 · NIAID · UNIVERSITY OF MISSOURI-COLUMBIA · PI WAN, XIUFENG HENRY · 2020 to 2025
$3.7M
Use of Clinical Samples to Identify Influenza Virus Antigenic VariantsR01AI147640 · NIAID · UNIVERSITY OF MISSOURI-COLUMBIA · PI WAN, XIUFENG HENRY · 2019 to 2024
$2.8M
Evolution, transmission, and clinical impacts of SARS-CoV-2 variants among urban and rural populationsF30AI172230 · NIAID · UNIVERSITY OF MISSOURI-COLUMBIA · PI TANG, CYNTHIA Y · 2022 to 2023
$65k
NIAID NIH HHS F30 AI172230NIAID NIH HHS R01 AI147640NIAID NIH HHS R01 AI152521
6 · The paper itself

Abstract

As SARS-CoV-2 and influenza viruses co-circulate, co-infections with these viruses generate an increasing concern to public health. To evaluate the prevalence and clinical impacts of SARS-CoV-2 and influenza A virus co-infections during the 2021-2022 influenza season, SARS-CoV-2-positive samples from 462 individuals were collected from October 2021 to January 2022. Of these individuals, 152 tested positive for influenza, and the monthly co-infection rate ranged from 7.1% to 48%. Compared to the Delta variant, individuals infected with Omicron were less likely to be co-infected and hospitalized, and individuals who received influenza vaccines were less likely to become co-infected. Three individuals had two samples collected on different dates, and all three developed a co-infection after their initial SARS-CoV-2 infection. This study demonstrates high prevalence of co-infections in central Missouri during the 2021-2022 influenza season, differences in co-infection prevalence between the Delta and the Omicron waves, and the importance of influenza vaccinations against co-infections.

Indexed as

CoinfectionCOVID-19Influenza A virusInfluenza, HumanInfluenza VaccinesCross-Sectional StudiesHumansMissouriSARS-CoV-2SeasonsInfluenza VaccinesCo-infectionH3N2Influenza a virusInfluenza vaccinationSARS-CoV-2SARS-CoV-2 variant

Identifiers

PMID36206606
PMCPMC9523501
OpenAlexW4298111859

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.