ArticleScience advances2022
Creating enzyme-mimicking nanopockets in metal-organic frameworks for catalysis.
Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed.
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- Selective photocatalytic oxidative cleavage of terminal alkynes to carboxylic acids within a water-soluble PdChemical science · 2026Article
- Creating hydrophobic nanopockets in metal-organic frameworks to promote hydrodeoxygenation of lignin derivatives under ambient conditions.Chemical science · 2025Article
- Sorting polymerization in a bichannel metal-organic framework.Nature communications · 2025Article
- Nanocavity in hollow sandwiched catalysts as substrate regulator for boosting hydrodeoxygenation of biomass-derived carbonyl compounds.Science advances · 2024Article
- Beyond nothingness in the formation and functional relevance of voids in polymer films.Nature communications · 2024Article
- 2D Graphene Oxide Membrane Nanoreactors for Rapid Directional Flow Ring-Opening Reactions with Dominant Same-Configuration Products.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- A Structural Mimic of Carbonic Anhydrase in Zeolitic Imidazolate Frameworks via Trans-functionalization for Enhancing Hydrolytic Activity.Research (Washington, D.C.) · 2024Article
- Dynamic self-assembly of supramolecular catalysts from precision macromolecules.Chemical science · 2023Article
- MOFganic Chemistry: Challenges and Opportunities for Metal-Organic Frameworks in Synthetic Organic Chemistry.Chemistry of materials : a publication of the American Chemical Society · 2023Article
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Authors and funding
10 authors.
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Abstract
Numerous efforts are being made toward constructing artificial nanopockets inside heterogeneous catalysts to implement challenging reactions that are difficult to occur on traditional heterogeneous catalysts. Here, the enzyme-mimetic nanopockets are fabricated inside the typical UiO-66 by coordinating zirconium nodes with terephthalate (BDC) ligands and monocarboxylate modulators including formic acid (FC), acetic acid (AC), or trifluoroacetic acid (TFA). When used in transfer hydrogenation of alkyl levulinates with isopropanol toward γ-valerolactone (GVL), these modulators endow zirconium sites with enhanced activity and selectivity and good stability. The catalytic activity of UiO-66FC is ~30 times that of UiO-66, also outperforming the state-of-the-art heterogeneous catalysts. Distinct from general consensus on electron-withdrawing or electron-donating effect on the altered activity of metal centers, this improvement mainly originates from the conformational change of modulators in the nanopocket to assist forming the rate-determining six-membered ring intermediate at zirconium sites, which are stabilized by van der Waals force interactions.
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