ArticleScience advances2022
An artificial intelligence enabled chemical synthesis robot for exploration and optimization of nanomaterials.
Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
62 citing papers in PubMed, 172 citations in OpenAlex.
- Machine Learning-Driven Nanoscale Synthesis for Electrocatalytic Performance: From Data-Driven Methodologies to Closed-Loop Optimization.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Surface Ligands in Nanocrystal Electrocatalysis: A Double-Edged Sword.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Analysis of Pharmacokinetic-Pharmacodynamic Relationships of Nanoparticles against Tumors.ACS nano · 2026Article
- Turning Unpredictable Biomolecule Adsorption to Controlled Corona Formation: Focus on Carbon Nanomaterials.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Chemputer and chemputation-A universal chemical compound synthesis machine.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Verification and execution of the scientific literature via chemputation augmented by large language models.Communications chemistry · 2026Article
- AP-Lab: An AI-Driven Autonomous Pilot-Scale Platform Bridging Materials Discovery and Industrial Manufacturing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Self-Controlled Automated Strategy for the Synthesis of Gold Nanorods With Fine-Tuned Longitudinal Absorption.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Article
- MODNet: A Monocular Object-Based Depth Estimation Network for AI Robotic Chemists.Precision chemistry · 2026Article
- Article
- Automated air plasma-assisted functionalization of graphite electrodes for enhanced electrochemical sensing of uric acid.Mikrochimica acta · 2026Article
- AI-driven robotic crystal explorer for rapid polymorph identification.Digital discovery · 2026Article
- Artificial Intelligence Empowered New Materials: Discovery, Synthesis, Prediction to Validation.Nano-micro letters · 2026Review
- Utilizing Similarity Measures to Map Chemical Reactivity.Angewandte Chemie (International ed. in English) · 2026Article
- Artificial Intelligence for Osteoporosis Diagnosis, Risk Prediction and Therapy: Current Advances, Clinical Challenges, and Future Perspectives.Clinical interventions in aging · 2026Review
- Metal-based nanomaterials for cancer phototherapy: current advancements and translational challenges.Frontiers in pharmacology · 2026Review
- Text-mined dataset of solid-state syntheses with impurity phases using Large Language Model.Scientific data · 2025Article
- AI-driven design of multifunctional nanomaterials in revolutionizing high-temperature, high-power solutions for space technology: potentials, challenges and perspectives.Discover nano · 2025Review
- Enhancing deep chemical reaction prediction with advanced chirality and fragment representation.Chemical communications (Cambridge, England) · 2025Article
- Automated Digital Discovery and Synthesis of CuO-Based Nanoparticle Heterostructures for Catalysis.ACS applied materials & interfaces · 2025Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We present an autonomous chemical synthesis robot for the exploration, discovery, and optimization of nanostructures driven by real-time spectroscopic feedback, theory, and machine learning algorithms that control the reaction conditions and allow the selective templating of reactions. This approach allows the transfer of materials as seeds between cycles of exploration, opening the search space like gene transfer in biology. The open-ended exploration of the seed-mediated multistep synthesis of gold nanoparticles (AuNPs) via in-line ultraviolet-visible characterization led to the discovery of five categories of nanoparticles by only performing ca. 1000 experiments in three hierarchically linked chemical spaces. The platform optimized nanostructures with desired optical properties by combining experiments and extinction spectrum simulations to achieve a yield of up to 95%. The synthetic procedure is outputted in a universal format using the chemical description language (χDL) with analytical data to produce a unique digital signature to enable the reproducibility of the synthesis.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.