Evidence map›Paper›PMID 36206265›Full record

ArticlePloS one2022

Cervical length distribution among Brazilian pregnant population and risk factors for short cervix: A multicenter cross-sectional study.

Kaline Gomes Ferrari Marquart, Thais Valeria Silva, Ben W Mol, José Guilherme Cecatti, Renato Passini, Cynara M Pereira, Thaísa B Guedes, Tatiana F Fanton, Rodolfo C Pacagnella, P5 working group

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Kaline Gomes Ferrari MarquartDepartment of Obstetrics and Gynecology, School of Medicine, University of Campinas, Campinas, São Paulo, Brazil.
Thais Valeria SilvaDepartment of Obstetrics and Gynecology, School of Medicine, University of Campinas, Campinas, São Paulo, Brazil.ORCID 0000-0002-8718-5372
Ben W MolDepartment of Obstetrics and Gynaecology, Monash University, Clayton, Victoria, Australia.
José Guilherme CecattiDepartment of Obstetrics and Gynecology, School of Medicine, University of Campinas, Campinas, São Paulo, Brazil.
Renato PassiniDepartment of Obstetrics and Gynecology, School of Medicine, University of Campinas, Campinas, São Paulo, Brazil.
Cynara M PereiraDepartment of Obstetrics and Gynecology, School of Medicine, University of Campinas, Campinas, São Paulo, Brazil.
Thaísa B GuedesDepartment of Obstetrics and Gynecology, School of Medicine, University of Campinas, Campinas, São Paulo, Brazil.
Tatiana F FantonDepartment of Obstetrics and Gynecology, School of Medicine, University of Campinas, Campinas, São Paulo, Brazil.
Rodolfo C PacagnellaDepartment of Obstetrics and Gynecology, School of Medicine, University of Campinas, Campinas, São Paulo, Brazil.ORCID 0000-0002-5739-0009
P5 working group
Universidade Estadual de Campinas (UNICAMP) · BRMonash University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveSince there are populational differences and risk factors that influence the cervical length, the aim of the study was to construct a populational curve with measurements of the uterine cervix of pregnant women in the second trimester of pregnancy and to evaluate which variables were related to cervical length (CL) ≤25 mm. MATERIALS AND

methodsThis was a multicenter cross-sectional study performed at 17 hospitals in several regions of Brazil. From 2015 to 2019, transvaginal ultrasound scan was performed in women with singleton pregnancies at 18 0/7 to 22 6/7 weeks of gestation to measure the CL. We analyzed CL regarding its distribution and the risk factors for CL ≤25 mm using logistic regression.

resultsThe percentage of CL ≤ 25mm was 6.67%. Shorter cervices, when measured using both straight and curve techniques, showed similar results: range 21.0-25.0 mm in straight versus 22.6-26.0 mm in curve measurement for the 5th percentile. However, the difference between the two techniques became more pronounced after the 75th percentile (range 41.0-42.0 mm straight x 43.6-45.0 mm in curve measurement). The risk factors identified for short cervix were low body mass index (BMI) (OR: 1.81 CI: 1.16-2.82), higher education (OR: 1.39 CI: 1.10-1.75) and personal history ([one prior miscarriage OR: 1.41 CI: 1.11-1.78 and ≥2 prior miscarriages OR: 1.67 CI: 1.24-2.25], preterm birth [OR: 1.70 CI: 1.12-2.59], previous low birth weight <2500 g [OR: 1.70 CI: 1.15-2.50], cervical surgery [OR: 4.33 CI: 2.58-7.27]). By contrast, obesity (OR: 0.64 CI: 0.51-0.82), living with a partner (OR: 0.76 CI: 0.61-0.95) and previous pregnancy (OR: 0.46 CI: 0.37-0.57) decreased the risk of short cervix.

conclusionsThe CL distribution showed a relatively low percentage of cervix ≤25 mm. There may be populational differences in the CL distribution and this as well as the risk factors for short CL need to be considered when adopting a screening strategy for short cervix.

Indexed as

Cervix UteriPremature BirthBrazilCervical Length MeasurementCross-Sectional StudiesFemaleHumansInfant, NewbornPregnancyPregnancy Trimester, SecondRisk Factors

Identifiers

PMID36206265
PMCPMC9544154
OpenAlexW4303449336

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.